Results 31 to 40 of about 38,630,120 (154)

The impact of physiological oxidants on triggering amyloid formation of the cell cycle regulator protein p16INK4A

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract The tumor suppressor protein p16INK4a plays a key role in cell cycle control and is frequently inactivated in human cancers. We previously discovered that oxidation of its single cysteine residue induces a structural transition from the functional monomeric form into inactive amyloid fibrils.
Briana R. Smith   +6 more
wiley   +1 more source

UEG Week 2022 Poster Presentations

open access: yes, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 473-1092, October 2022.
wiley   +1 more source

Acetylcholinesterase: Structure, dynamics, and interactions with organophosphorus compounds

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract Acetylcholinesterase (AChE) is an enzyme that hydrolyzes the neurotransmitter acetylcholine (ACh), removing it from the synaptic cleft after the transmission of an electrical signal, making it an essential component of chemical neurotransmission. AChE is a serine hydrolase, containing a catalytic triad of Ser/His/Glu.
Li‐Wei Hung   +3 more
wiley   +1 more source

The role of the brain–gut–microbiota axis in psychology: The importance of considering gut microbiota in the development, perpetuation, and treatment of psychological disorders

open access: yesBrain and Behavior, Volume 9, Issue 11, November 2019., 2019
Gut microbiota are proposed to influence mood, cognition, and behavior both directly and indirectly. This offers a new approach to conceptualizing psychological disorders from predisposition through to treatment. While not suggesting that targeting the gut microbiota is the panacea to all psychological conditions, it does offer an exciting new arm to a
Michael Ganci   +3 more
wiley   +1 more source

Adherence to Physical Activity and Incident Mobility Disability in Older Adults With Mobility Limitations

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Preservation of mobility independence is a primary goal in older adults with physical frailty and sarcopenia (PF&S). Interventions based on the combination of physical activity (PA) and nutritional counselling have been indicated as strategies for the management of this condition, although their effectiveness is not confirmed in all
Alejandro Álvarez‐Bustos   +24 more
wiley   +1 more source

UEG Week 2021 Oral Presentations

open access: yes, 2021
United European Gastroenterology Journal, Volume 9, Issue S8, Page 7-161, October 2021.
wiley   +1 more source

Angel and son – Witkiewicz-father`s persona and his relationship with son [PDF]

open access: yes, 2018
W artykule Autorka prezentuje Stanisława Witkiewicza w jednej z jego prywatnych ról – w roli ojca. Pokazuje, jakie relacje łączyły ojca z jedynym synem – Stanisławem Ignacym, jak układały się stosunki pomiędzy tymi dwiema wybitnymi osobowościami, jak ...
Majewska-Wójcik, Anna Magdalena
core   +2 more sources

Exploring the Common Mutational Landscape in Cutaneous Melanoma and Pancreatic Cancer

open access: yesPigment Cell &Melanoma Research, Volume 38, Issue 1, January 2025.
ABSTRACT Cutaneous melanoma (CM) and pancreatic cancer are aggressive tumors whose incidences are rapidly increasing in the last years. This review aims to provide a complete and update description about mutational landscape in CM and pancreatic cancer, focusing on similarities of these two apparently so different tumors in terms of site, type of cell ...
Elisabetta Broseghini   +9 more
wiley   +1 more source

Stanisław I. Witkiewicz o obiektywizacji uczuć metafizycznych [PDF]

open access: yes
The article presents Witkiewicz’s views on metaphysical feelings as a source of culture in its three manifestations: art, religion and philosophy.
Nowak, Witold M.
core   +1 more source

Konferencja „Stanisław Ignacy Witkiewicz. Konteksty filozoficzne, teatralne i filmowe”, Instytut Filozofii, Instytut Literatury Polskiej, Uniwersytet Wrocławski, 19–20 listopada 2015 [PDF]

open access: yes, 2019
Conference „Stanisław Ignacy Witkiewicz in Contexts. Philosophy, Theatre, and Film”. Institute of Philosophy, Institute of Polish Literature, University of Wrocław, November 19-20, 2015Konferencja „Stanisław Ignacy Witkiewicz.
Dombrowski, Maciej
core  

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