Results 121 to 130 of about 29,623 (214)

S100A4 Orchestrates Fibroblast Fate to Drive Fibrotic Remodeling

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Fibrotic stimuli induce S100A4 expression, promoting the activation of apoptosis‐resistant fibroblasts through engagement of ERK‐associated signaling. In fibroblasts, S100A4 orchestrates fibroblast fate by enhancing migration, promoting stress fiber formation, increasing ECM contractility, upregulating α‐SMA expression, and supporting survival ...
Spring Li, Banruo Cai, Xu Zhang, Guoqiang Cai, Yong Zhou, Brant M. Wagener, Qiang Ding   +6 more
wiley   +1 more source

1H NMR assignments of apo calcyclin and comparative structural analysis with calbindin d(9k) and s 100β

, 1996
The homodimeric S100 protein calcyclin has been studied in the apo state by two-dimensional 1H NMR spectroscopy. Using a combination of scalar correlation and NOE experiments, sequence-specific 1H NMR assignments were obtained for all but one backbone ...
Potts, Barbara C.M.,, Chazin, Walter J., Hidaka, Hiroyoshi, Carlström, Göran, Okazaki, Katsuo, Carlström, Göran,, Okazaki, Katsuo,, Göran Carlström, Hiroyoshi Hidaka, Potts, Barbara C.M., Chazin, Walter J.,, Barbara C.M. Potts, Katsuo Okazaki, Hidaka, Hiroyoshi,, Lund University., Walter J. Chazin   +15 more
core   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1327-1338, June 2026.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

The calcium-dependent interactions of p53 and other intrinsically disordered peptides with members of the S100 protein family.

, 2013
August 2013School of ScienceUnderstanding the molecular recognition that occurs during protein-protein interactions is one of the fundamental goals of biochemistry.
Wafer, Lucas N. R.
core  

Ca2+ /S100 regulation of giant protein kinases

, 1996
Protein phosphorylation by protein kinases plays a central regulatory role in cellular processes and these kinases are themselves tightly regulated(1).
Heierhorst, Jörg, Susanne C. Feil, Kobe, Bostjan, Feil, Susanne C., Jörg Heierhorst, Michael W. Parker, Bruce E. Kemp, Kemp, Bruce E., Bostjan Kobe, Guy M. Benian, Klaudiusz R. Weiss, Weiss, Klaudiusz R., Parker, Michael W., Benian, Guy M.   +13 more
core   +1 more source

Programmed Cell Death in Chronic Rhinosinusitis

Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu, Junying Hu, Weigang Gan, Qi Wu, Bing Zhong, Feng Liu   +5 more
wiley   +1 more source

RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi, Giulia Gentili, Laura Salvadori, Martina Paiella, Marcello Manfredi, Vittoria Federica Borrini, Kaamashri Mangar, Ann Marie Schmidt, Maurizio Muscaritoli, Francesca Riuzzi, Guglielmo Sorci   +10 more
wiley   +1 more source

Nível sérico da proteína S100B em pacientes com epilepsia secundária a neurocisticercose. [PDF]

, 2000
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Broering, Felipe Eduardo
core  

Binding of S100 proteins to RAGE: an update

, 2009
The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand receptor of the immunoglobulin family. RAGE interacts with structurally different ligands probably through the oligomerization of the receptor on the cell surface.
Fritz, G, Vetter, Stefan W., Heizmann, Claus W., Stefan W. Vetter, Heizmann, C W, Estelle Leclerc, Günter Fritz, Claus W. Heizmann, Fritz, Günter, Vetter, S W, Leclerc, Estelle, Leclerc, E   +11 more
core   +1 more source

EV‐SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
This study introduces ‘EV‑SPEC’, a spatial proteomics method using TurboID fused to the transmembrane protein CD63 to map the protein corona of extracellular vesicles (EVs) without physical isolation. We show that EV‐SPEC identifies the protein‐protein interaction footprint of serum proteins, similar to those typically found on synthetic nanoparticles,
Camille Menaceur Vandenbroucke, Carsten Scavenius, Yuya Hayashi   +2 more
wiley   +1 more source