Results 141 to 150 of about 29,623 (214)

Integration of Transcriptomics With Interpretable Artificial Intelligence for Identifying Molecular Signatures of Physiological Stress in Sleep Deprivation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Sleep deprivation induces systemic physiological stress accompanied by transcriptomic remodelling and immune dysregulation, yet objective molecular indicators for its assessment remain insufficient. This study integrated blood transcriptomic analysis with an interpretable machine learning framework to identify and validate candidate molecular ...
Kun Wang, Qiang Zong, Chengcheng Wang, Peng Wang, Zhenhao Shuai, Min Wu, Yuming Peng, Junying Zhou, Jianwei Shuai, Fangfu Ye, Aimin Wu, Yanyan Zheng   +11 more
wiley   +1 more source

Calcium Buffering in Astrocytes and Its Relevance for Experimental Data Interpretation and Computational Modeling

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Components and properties of Ca2+ buffers in astrocytes, which should be considered for data interpretation and in computational modeling of astrocyte Ca2+ activity. ABSTRACT Astrocytic Ca2+ signaling is essential for maintaining physiological brain function, including the modulation of synaptic transmission, neurovascular coupling, and ion homeostasis.
Kerstin Lenk, Andre Zeug, Franziska E. Müller   +2 more
wiley   +1 more source

Functions of S100 proteins

, 2013
The S100 protein family consists of 24 members functionally distributed into three main subgroups: those that only exert intracellular regulatory effects, those with intracellular and extracellular functions and those which mainly exert extracellular ...
DONATO, Rosario Francesco, Cannon B. R., Weber D. J., Geczy C. L., SORCI, Guglielmo, RIUZZI, Francesca, Hsu K.   +6 more
core  

Novel interactions of the TRTK12 peptide with S100 protein family members: specificity and thermodynamic characterization. [PDF]

Biochemistry, 2013
Wafer LN, Tzul FO, Pandharipande PP, Makhatadze GI.   +3 more
europepmc   +1 more source

Quantification of neurodegeneration by measurement of brain-specific proteins

, 2003
Quantification of neurodegeneration in animal models is typically assessed by time-consuming and observer-dependent immunocytochemistry. This study aimed to investigate if newly developed ELISA techniques could provide an observer-independent, cost ...
Baker, D., Petzold, A., Pryce, G., Thompson, E.J., Keir, G., Giovannoni, G.   +5 more
core  

A multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours. [PDF]

BMC Cancer, 2015
Martínez-Aguilar J, Clifton-Bligh R, Molloy MP.   +2 more
europepmc   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

A first structural model for covalent dimerization of S100 proteins. [PDF]

Acta Crystallogr F Struct Biol Commun
Demou M, Yatime L.
europepmc   +1 more source

Cancer-associated fibroblast-derived protein S100-A11 influences the response to anti-HER2 therapies in HER2-positive breast cancer. [PDF]

Neoplasia
Luque M, Morales-Gallego M, Sanz-Álvarez M, Arguiñano C, Rangel Y, Ramírez-Merino N, Qin M, Rovira A, Albanell J, Madoz-Gúrpide J, Rojo F.   +10 more
europepmc   +1 more source

The Role of Neutrophil, Monocyte and Macrophage Calprotectin and S100A12 in the Fibrotic Process. [PDF]

Biomolecules
Regino-Zamarripa NE, Burciaga AS, Bocanegra-Mondragón M, Cruz-Lagunas A, Camarena Á, Jiménez-Alvarez L, Ramírez R, Ramírez-Martínez G, Zúñiga J.   +8 more
europepmc   +1 more source