Results 181 to 190 of about 29,623 (214)

The S100 protein family

Trends in Biochemical Sciences, 1988
Abstract The S100 proteins are a group of small Ca 2+ -binding modulator proteins involved in cell cycle progression, cell differentiation, and cytoskeletal-membrane interactions. Recently, many new members of the S100 protein family have been described.
Douglas Kligman
exaly   +3 more sources

S100 protein family and embryo implantation

Journal of Cellular Biochemistry, 2019
AbstractIt is well known that embryo implantation is a critical process in which embryo should be able to reach and attach to endometrium. Until now, various types of factors are involved in the regulation of this process. S100 proteins are calcium‐binding proteins, which have vital roles in embryo implantation and have been considered as possible ...
Aynaz Mihanfar, Amir Fattahi, Zeinab Latifi   +2 more
exaly   +3 more sources

A review of S100 protein family in lung cancer

Clinica Chimica Acta, 2018
S100 protein family, representing 25 relatively small calcium binding proteins, has been reported to be involved in multiple stages of tumorigenesis and progression. These proteins are considered having potential value to be adopted as novel biomarkers in the detection and accurate prediction of many kinds of tumors, including lung cancer.
Ting, Wang, Xiaoying, Huo, Zhaoyang, Chong, Hamadhaider, Khan, Rui, Liu, Ting, Wang   +5 more
exaly   +3 more sources

Multifarious diagnostic possibilities of the S100 protein family: predominantly in pediatrics and neonatology

World Journal of Pediatrics, 2018
Numerous articles related to S100 proteins have been recently published. This review aims to introduce this large protein family and its importance in the diagnostics of many pathological conditions in children and adults.Based on original publications found in database systems, we summarize the current knowledge about the S100 protein group and ...
Josef Srovnal, Jana Volejníková, Vladimir Mihal   +2 more
exaly   +3 more sources

S100 and S100 fused-type protein families in epidermal maturation with special focus on S100A3 in mammalian hair cuticles

Biochimie, 2011
Epithelial Ca(2+)-regulation, which governs cornified envelope formation in the skin epidermis and hair follicles, closely coincides with the expression of S100A3, filaggrin and trichohyalin, and the post-translational modification of these proteins by Ca(2+)-dependent peptidylarginine deiminases.
Kizawa, K, Takahara, H, Unno, M, Heizmann, C W   +3 more
openaire   +4 more sources

Expression of S100 protein family members in the pathogenesis of bladder tumors.

Anticancer research, 2007
The S100 proteins act as multifactional signaling factors that are involved in the regulation of diverse cellular processes. To explore the involvement of S100 genes in bladder cancers, S100 gene expressions were systematically evaluated at the RNA level by microarray and real-time PCR. Total RNAs were obtained from 4-hydroxybutyl(butyl)nitrosamine (OH-
Ruisheng, Yao, Antonio, Lopez-Beltran, Gregory T, Maclennan, Rodolfo, Montironi, John N, Eble, Liang, Cheng   +5 more
openaire   +2 more sources

The Multifunctional S100 Protein Family

2002
Claus W Heizmann, Heizmann Claus W
exaly   +2 more sources

Role of the S100 protein family in liver disease (Review)

International Journal of Molecular Medicine, 2021
Liver disease is a significant health challenge worldwide and comprises liver fibrosis and cirrhosis, viral hepatitis, fatty liver, non‑alcoholic fatty liver disease, alcoholic liver disease and hepatocellular carcinoma (HCC). Due to the lack of effective treatments, the prognosis of end‑stage liver disease (including advanced liver cirrhosis and HCC ...
Shun, Yao, Xingyue, Yang, Jiaxing, An, Hai, Jin, Guorong, Wen, Hui, Wang, Biguang, Tuo   +6 more
openaire   +2 more sources

S100 family proteins in inflammation and beyond

2020
The S100 family proteins possess a variety of intracellular and extracellular functions. They interact with multiple receptors and signal transducers to regulate pathways that govern inflammation, cell differentiation, proliferation, energy metabolism, apoptosis, calcium homeostasis, cell cytoskeleton and microbial resistance.
Gopalkrishna, Sreejit, Michelle C, Flynn, Mallikarjun, Patil, Prasanna, Krishnamurthy, Andrew J, Murphy, Prabhakara R, Nagareddy   +5 more
openaire   +2 more sources

Specific cytokines of interleukin-6 family interact with S100 proteins

Cell Calcium, 2022
Cytokines of interleukin-6 (IL-6) family are important signaling proteins involved in various physiological and pathological processes. Earlier, we described interactions between IL-11 and S100P/B proteins from the family of S100 proteins engaged in the pathogenesis of numerous diseases.
Kazakov, Alexey S., Sokolov, Andrey S., Permyakova, Maria E., Litus, Ekaterina A., Uversky, Vladimir N., Permyakov, Eugene A., Permyakov, Sergei E.   +6 more
openaire   +3 more sources