Results 151 to 160 of about 38,415 (238)

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

The Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu, Andrew E. Worthy, Alan J. Emanuel   +2 more
wiley   +1 more source

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

International Journal of Cancer, Volume 159, Issue 11, Page 2824-2834, 1 December 2026.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött, Glenn Geidel, Carmen M. T. Roeper, Lucija Ačkar, Bente Siebels, Hannah Voß, Hartmut Schlüter, Michaela Schweizer, Kilian Müller, Alessandra Rünger, Tim Zell, Benjamin Deitert, Ali Zeinal‐Abedini, Isabel Heidrich, Stefan W. Schneider, Klaus Pantel, Daniel J. Smit, Christoffer Gebhardt   +17 more
wiley   +1 more source

Assessment of faecal calprotectin in neonatal calf diarrhoea using a human ELISA kit: Associations with faecal score and serum biochemical markers

Veterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diarrhoea in newborn calves, which occurs in the first month of life and is caused by various pathogens, poses a significant threat to livestock industries. Therefore, timely diagnosis of enteritis in calves can be advantageous. Objective This study aimed to determine the efficacy of faecal calprotectin as a biomarker indicating ...
Narges Lotfalizadeh, Farima Jahromi, Alborz Yadollahi, Saeed Nazifi   +3 more
wiley   +1 more source

S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis. [PDF]

Arthritis Res Ther
Brunner HI, Schulert GS, Sproles A, Thornton S, Cornejo GV, Antón J, Cuttica R, Henrickson M, Foeldvari I, Kingsbury DJ, Askelson M, Liu J, Mukherjee S, Wong RL, Lovell DJ, Martini A, Ruperto N, Grom AA, Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organisation (PRINTO).   +18 more
europepmc   +1 more source

Fundamentals, Advances, and Applications of Electrospun Nanofibrous 3D Materials

Journal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Three‐dimensional electrospun nanofibrous systems offer unique properties and microenvironments. These properties are determined by the fabrication strategies employed and can be adjusted by the incorporation of functional additives to achieve multifunctionality for specific applications. The applications range from the biomedical to the environmental,
Rebecca Hengsbach, Viraj P. Nirwan, Altangerel Amarjargal, Zahra Asefi, Amir Fahmi   +4 more
wiley   +1 more source

Preanalytical variables affect predictive immunohistochemical biomarker testing in non–small cell lung carcinoma cytology specimens

Cancer Cytopathology, Volume 134, Issue 11, November 2026.
Abstract Background Several therapeutic targets for non–small cell lung carcinoma (NSCLC) rely on protein expression by immunohistochemistry (IHC). Most biomarkers are validated on formalin‐fixed, paraffin‐embedded (FFPE) tissue; however, cytologic specimens, including cell blocks (CBs), that are subject to preanalytical variables are increasingly used.
Saroja Devi Geetha, Wei‐Lien Wang, Neda Kalhor, Sinchita Roy‐Chowdhuri   +3 more
wiley   +1 more source

Correction: S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis. [PDF]

Arthritis Res Ther
Brunner HI, Schulert GS, Sproles A, Thornton S, Cornejo GV, Antón J, Cuttica R, Henrickson M, Foeldvari I, Kingsbury DJ, Askelson M, Liu J, Mukherjee S, Wong RL, Lovell DJ, Martini A, Ruperto N, Grom AA, Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organisation (PRINTO).   +18 more
europepmc   +1 more source

Comprehensive Evaluation of Gastrointestinal Factors Influencing the Stability and Function of mRNA‐Encapsulated Lipid Nanoparticles

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Owing to the intrinsic instability of mRNA, its routes of administration are limited, and to date, only injectable delivery has been clinically applied. In contrast, oral administration exposes mRNA to a variety of substances in the gastrointestinal (GI) tract.
Toma Shinkai, Koki Ogawa, Mohamed S. Mohamed, Tetsuya Ozeki   +3 more
wiley   +1 more source

Protein S100-A6 [PDF]

, 2020
openaire   +1 more source

Microarray analysis of gene expression in lung tissues of indium-exposed rats: possible roles of S100 proteins in lung diseases. [PDF]

Arch Toxicol
Hiraku Y, Tanaka A, Yamamoto M, Nakatani M, Kobayashi M, Kimura E, Ahmed S, Murata M.   +7 more
europepmc   +1 more source