Results 101 to 110 of about 3,737,571 (308)
Four pillars of the S-phase checkpoint [PDF]
Genes & Development, 2013 The yeast Mec1 kinase is a key regulator of the DNA damage response (DDR). In this issue of Genes & Development, Kumar and Burgers (pp. 313–321) report that Ddc1, Dpb11, and Dna2 function in concert to activate Mec1 during S phase of the cell cycle.
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 1998 Checkpoints that respond to DNA structure changes were originally defined by the inability of yeast mutants to prevent mitosis following DNA damage or S-phase arrest.
Per U Christensen (16064291) +7 more
core
R-Phycoerythrin Induces SGC-7901 Apoptosis by Arresting Cell Cycle at S Phase
Marine Drugs, 2016 R-Phycoerythrin (R-PE), one of the chemical constituents of red algae, could produce singlet oxygen upon excitation with the appropriate radiation and possibly be used in photodynamic therapy (PDT) for cancer.
Huixin Tan +7 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Estimating the phase congruency of localised frequencies
, 2004 Phase congruency is a new method for detecting features in images. One of its significant strengths is its invariance to lighting variation within an image, as well as being able to detect a wide range of interesting features.
Myerscough, Peter J, Nixon, Mark S
core
Investigation of simultaneous 2R regeneration of two 40 Gb/s channels in a single optical fiber [PDF]
, 2008 We experimentally investigate the simultaneous all-optical signal processing of two 40-Gb/s wavelength-division multiplexing optical streams spaced by ~5 nm using self-phase modulation and offset filtering in a single highly nonlinear fiber to achieve a ...
Provost, L. +3 more
core +1 more source
$\eta/s$ and Phase Transitions [PDF]
, 2008 Comment: Revised for PRD. Shorter (by one section) than first version.
Dobado González, Antonio +2 more
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
S phase block following MEC1ATR inactivation occurs without severe dNTP depletion
Biology Open, 2015 Inactivation of Mec1, the budding yeast ATR, results in a permanent S phase arrest followed by chromosome breakage and cell death during G2/M. The S phase arrest is proposed to stem from a defect in Mec1-mediated degradation of Sml1, a conserved ...
Caroline Earp +4 more
doaj +1 more source