Results 11 to 20 of about 3,737,571 (308)

Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Frontiers in Genetics, 2023
Immune checkpoint inhibition for the treatment of cancer has provided a breakthrough in oncology, and several new checkpoint inhibition pathways are currently being investigated regarding their potential to provide additional clinical benefit.
Annie Borch, Anne-Mette Bjerregaard, Anne-Mette Bjerregaard, Vinicius Araujo Barbosa de Lima, Olga Østrup, Christina Westmose Yde, Aron Charles Eklund, Morten Mau-Sørensen, Carolina Barra, Inge Marie Svane, Finn Cilius Nielsen, Finn Cilius Nielsen, Samuel A. Funt, Ulrik Lassen, Sine Reker Hadrup   +14 more
doaj   +1 more source

The NUCKS1-SKP2-p21/p27 axis controls S phase entry

Nature Communications, 2021
Entry into S phase of the cell cycle is regulated positively by mitogens and negatively by DNA damage; however, how balance of these signals is achieved is not well known.
Samuel Hume, Claudia P. Grou, Pauline Lascaux, Vincenzo D’Angiolella, Arnaud J. Legrand, Kristijan Ramadan, Grigory L. Dianov   +6 more
doaj   +1 more source

Regulation in S Phase by E2F [PDF]

Cell Cycle, 2004
The DNA synthetic S phase of the unperturbed cell cycle is a closed system, as compared to regulation of G(1) by external growth factors. The E2F family provides internal control in S phase by transcribing genes required for deoxynucleotide triphosphate (dNTP) and DNA synthesis.
Arthur B, Pardee, Chiang J, Li, G Prem Veer, Reddy   +2 more
openaire   +2 more sources

Homodyne coherent detection of ASK and PSK signals performed by a subcarrier optical phase-locked loop [PDF]

, 2005
Optical transmission systems based on homodyne coherent detection of 2-ASK and pilot carrier 2-PSK signals have been implemented. ASK data has been transmitted at 2.5 Gbps, while 2.5 Gbps and 10 Gbps PSK systems have been tested.
S. Camatel, Ferrero, Valter, CAMATEL S, V. Ferrero, Camatel, S.   +4 more
core   +1 more source

INSTRUMENTED MICROSCRATCH TESTS USAGE FOR STUDY OF EXPANDED AUSTENITE PROPERTIES [PDF]

Tecnologia em Metalurgia, Materiais e Mineração, 2015
Corrosion resistance and poor mechanical properties are both characteristics of AISI 316 austenitic stainless steel. Nitrogen supersaturated expanded austenite, or S-phase, promotes surface hardening of the alloy without the formation of undesirable ...
Fernando Luis Sato, Luis Armando Espitia, Carlos Eduardo Pinedo , André Paulo Tschiptschin   +3 more
doaj   +1 more source

Regulating liquid and solid-state electrolytes for solid-phase conversion in Li–S batteries

, 2022
The solid-phase conversion mechanism in lithium–sulfur (Li–S) batteries has emerged with many attractive advantages such as avoiding the parasitic “shuttle effect” of soluble polysulfides and allowing lean electrolyte operating conditions.
Chao Xing, Ameer Nizami, Hao Chen, Zhang, S, Shanqing Zhang, Xing, C, Nizami, A, Lai, C, Shangshu Qian, Chao Lai, Xia Li, Qian, S, Wu, Z, Li, X, Chen, H, Zhenzhen Wu   +15 more
core   +1 more source

Cyclin A2: a genuine cell cycle regulator?

Biomolecular Concepts, 2012
Cyclin A2 belongs to the core cell cycle regulators and participates in the control of both S phase and mitosis. However, several observations suggest that it is also endowed with other functions, and our recent data shed light on its involvement in ...
Bendris Nawal, Loukil Abdelhalim, Cheung Caroline, Arsic Nikola, Rebouissou Cosette, Hipskind Robert, Peter Marion, Lemmers Bénédicte, Blanchard Jean Marie   +8 more
doaj   +1 more source

Exploring Challenges and Enablers of Sustainable Supply Chains in Indian Automotive SMEs for Enhancing Long-Term Competitiveness [PDF]

JES: Journal of Engineering Sciences
This study explores the contribution of Indian automotive Small and Medium Enterprises (SMEs) in progressing Sustainable Supply Chain Management (SSCM) through the Triple Bottom Line (TBL) framework by focusing on economic, environmental, and social ...
VIJAYA KUMAR S, Suresh R
doaj   +1 more source

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. [PDF]

, 2011
BACKGROUND\ud \ud An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries.\ud \ud METHODS\ud \ud From March 2009 through January 2011, we enrolled 15,460 ...
Machera, Francisca, Abdulla, Salim, Sillman, Marla, Maingi, Charity, Aide, Pedro, Hamad, AS, Sambian, D, Kremsner, Peter Gottfried, Mordmüller, B, Conzelmann, Cornelia, Maingi, C, Sylverken, J, Adjei, George, Sandrine, Y, Abdul, Omari, Owusu-Ofori, R, Drakeley, C, Ansong, D, Leach, Amanda, Urassa, AM, Radford, A, Kayan, K, Methogo, Barbara Gaelle Nfono Ondo, Carter, T, Bejon, Philip, Gondi, Stacey, Chome, Nelecy, Akoo, P, Doucka, Yannick, Aponte, John J, Guerra, Yolanda, Aponte, JJ, Valea, I, Chandramohan, Daniel, null null, Alonso, P, Jones, David, Liheluka, Edwin, Sillman, M, Loucq, Christian, Malabeja, A, Omoto, Jackton, Agnandji, ST, Nyakuipa, Dalitso, Quelhas, D, Flamen, Arnaud, Jongert, Erik, Ahmed, S, Otieno, Walter, Bassat, Quique, Slutsker, L, Mordmüller, Benjamin, Slutsker, Laurence, Agyekum, Alex, Ofori-Anyinam, Opokua, Kaboré, W, Hamad, Ali Said, Doucka, Y, Wasuna, Ruth, Vansadia, Preeti, Otieno, A, Tahita, MC, Savarese, B, Lanaspa, Miguel, Ogutu, B, Gitaka, J, Lang, T, Drakeley, Chris, Issifou, S, Shomari, M, Abdul, O, Otieno, L, Otieno, K, Nyakuipa, D, Kaboré, William, Asante, Isaac, Gesase, Samwel, Cohen, Joe, Aide, P, Shubis, Kafuruki, Ogutu, Bernhards, Agnandji, Selidji Todagbe, Otieno, Lucas, Sambian, David, Kilavo, H, Adjei, S, Greenwood, B, Ansong, Daniel, Lell, Bertrand, Chandramohan, D, Awino, Norbert, Asante, KP, Rettig, T, Adjei, G, Gitaka, Jesse, Carter, Terrell, Juma, Omar, Gondi, S, Ouédraogo, JB, Tinto, H, Lemnge, M, Shomari, Mwanajaa, Guiguemdé, RT, Hoffman, Irving, Mvalo, T, Mtoro, Ali, Schellenberg, David, Quelhas, Diana, Radford, Afiya, Minja, Rose, Lievens, M, Cohen, J, Sorgho, H, Kerubo, Christine, Bawa, J, Theander, Thor, Ahmed, Saumu, Juma, O, Odero, Chris, Vekemans, Johan, Nkomo, Ruthendo, Muturi-Kioi, Vincent, Mvalo, Tisungane, RTS,S Clinical Trials Partnership, Theander, T, Tsofa, Benjamin, Dosoo, David, Ouédraogo, Jean Bosco, Mwangoka, Grace, Kremsner, PG, Jumbe, A, Otieno, W, Boateng, HO, Jongert, E, Rettig, Theresa, Conzelmann, C, Sorgho, Hermann, Flamen, A, Lell, B, Bejon, P, Ouédraogo, Sayouba, Osei-Kwakye, Kingsley, Agbenyega, Tsiri, Owira, Victorine, Nekoye, O, Issifou, Saadou, Muturi-Kioi, V, Ayamba, S, Kariuki, Simon, Methogo, BG, Oneko, Martina, Otieno, Kephas, Olotu, Ally, Lapierre, Didier, Fernandes, José Francisco, Macete, E, Owira, V, Ali, Ali Mohammed, Boahen, Owusu, Minja, R, Oneko, M, Onyango, Agnes Akoth, Leach, A, Liheluka, E, Sylverken, Justice, Lusingu, J, Hamel, Mary J, Salim, N, Vansadia, P, Owusu-Agyei, S, Njuguna, P, Kamthunzi, P, Macete, Eusébio, Mwangoka, G, Asante, Kwaku Poku, Owusu-Agyei, Seth, Fernandes, JF, Lemnge, Martha, Chintedza, J, Nhamuave, A, Ayamba, Samuel, Hamel, MJ, Msika, Albans, Kayan, Kingsley, Leboulleux, D, Alonso, Pedro, Kamthunzi, Portia, Marsh, K, Otieno, Allan, Kerubo, C, Ballou, W Ripley, Nekoye, Otsyula, Lanaspa, M, Shubis, K, Lievens, Marc, Sykes, A, Abossolo, Béatrice Peggy, Lapierre, D, Mandjate, Sofia, Chome, N, Ofori-Anyinam, O, Dosoo, D, Martinson, F, Marsh, Kevin, Urassa, Alwisa Martin, Mahende, Coline, Abdulla, S, Tsofa, B, Ali, AM, Boahen, O, Bassat, Q, Bawa, John, Sandrine, Yara, Osei-Kwakye, K, Peshu, N, Akoo, Pauline, Adjei, Samuel, Njuguna, Patricia, Jumbe, Allan, Williamson, John, Agbenyega, T, Sacarlal, J, Mtoro, A, Leboulleux, Didier, Greenwood, Brian, Malabeja, Anangisye, Wasuna, R, Chilengi, Roma, Schellenberg, D, Nhamuave, Arlindo, Guiguemdé, Robert Tinga, Awino, N, Tinto, Halidou, Tahita, Marc Christian, Mandjate, S, Asante, I, Martinson, Francis, Abossolo, BP, Tanner, M, Williamson, J, Kariuki, S, Machera, F, Kilavo, Hassan, Jones, D, Lusingu, John, Boateng, Harry Owusu, Chintedza, Joseph, Soulanoudjingar, Solange Solmeheim, Lang, Trudie, Sacarlal, Jahit, Gesase, S, Mahende, C, Ouédraogo, S, Bruls, Myriam, Guerra, Y, Msika, A, Soulanoudjingar, SS, Loucq, C, The RTS, S. Clinical Trials Partnership, Sykes, Alma, Agyekum, A, Owusu, L, Vekemans, J, Owusu, Larko, Odero, C, Tanner, Marcel, Laserson, Kayla F, Peshu, Norbert, Savarese, Barbara, Owusu-Ofori, Ruth, Omoto, J, Valea, Innocent, Chilengi, R, Bruls, M, D'Alessandro, Umberto, Onyango, AA, Hoffman, I, Salim, Nahya, Laserson, KF, D'Alessandro, U, Ballou, WR, Nkomo, R, Olotu, A   +282 more
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Engineering Design and Functional Evaluation of a Finger Millet Thresher with Integrated Dehusker [PDF]

JES: Journal of Engineering Sciences
This research highlights India’s agricultural innovation through the mechanization of finger millet threshing for smallholder farmers. The study focused on the development and evaluation of a finger millet thresher integrated with a Dehusking mechanism ...
Balappa U, Dayananda B S, Dinesh P A, Suresh R   +3 more
doaj   +1 more source