In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity [PDF]
The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin-tetrazolyl and -thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of ...
Andrade, Joana M. +9 more
core +1 more source
Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
core +2 more sources
Unexpected nucleophilic participation and rearrangement of DBU in reactions with saccharin derivatives [PDF]
DBU attacks saccharin derivatives with subsequent rearrangement to give rise to 3-[3'-(1"-azepin-2"-onyl)propylamino]-1,2-benzisothiazole-1,1-dioxide 2 after work ...
Barkley, James V. +3 more
core +1 more source
A Review: Saccharin Discovery, Synthesis, and Applications
Saccharin is firstly synthesized in 1879. It is a very well-known as an inexpensive substitute for sugar as it is a non-caloric sweetener. The article shows the properties, use, metabolism and various synthesis and reactions of saccharine. Moreover,
Ammar A. Razzak Mahmood +1 more
doaj +1 more source
Background: Rhodamin B and saccharin are chemicals that are harmful to the health of the body. Consumption of rhodamine B and saccharin for a long time can cause problems for the body such as impaired organ function.
Dzakiyyah Salmaa +5 more
doaj +1 more source
The synthesis and characterization of polypeptide-adriamycin conjugates and its complexes with adriamycin. Part I [PDF]
Poly(α-l-glutamic acid) (PGA) was grafted with amino acid and oligopeptide spacers up to 5 amino acids with the use of N,N'-carbonyldiimidazole and 2,3-dihydro-1,2-benz-isothiazole-3-on-1, 1-dioxide (saccharin) as an additive, and these polypeptides were
Eenink, M.J.D. +5 more
core +2 more sources
Rapid and label-free detection of saccharin in fresh jujube fruit
Saccharin is one of the oldest artificial sweeteners used in food industries because it has no calories. However, the abuse of saccharin is illegal.According to the National Standard of China, the maximum permitted level is 8.189×10-4 mol·L-1 in food. In
WU Hao +4 more
doaj +1 more source
The glycaemic effects of single doses of Panax ginseng in young healthy volunteers [PDF]
The results of two acute placebo-controlled, double-blind cross-over studies assessing the effect of Panax ginseng (G115) on blood glucose levels are reported.
Kennedy, David +2 more
core +1 more source
Carcinogenicity of saccharin. [PDF]
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis than female rats. Rats exposed as fetuses develop neoplasms more readily than rats exposed as
openaire +3 more sources
In order to get the information regarding the sweetener-water and sweetener-sweetener interactions, densities of sodium saccharin in water and (0.1, 0.3, and 0.5) m fructose have been measured at (298.15, 303.15, 308.15, and 313.15) K by the use of ...
Sanjeevan J. Kharat, Sachin M. Munde
doaj +3 more sources

