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A Review: Saccharin Discovery, Synthesis, and Applications
Saccharin is firstly synthesized in 1879. It is a very well-known as an inexpensive substitute for sugar as it is a non-caloric sweetener. The article shows the properties, use, metabolism and various synthesis and reactions of saccharine. Moreover,
Ammar A. Razzak Mahmood +1 more
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Carcinogenicity of saccharin. [PDF]
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis than female rats. Rats exposed as fetuses develop neoplasms more readily than rats exposed as
openaire +3 more sources
Rapid and label-free detection of saccharin in fresh jujube fruit
Saccharin is one of the oldest artificial sweeteners used in food industries because it has no calories. However, the abuse of saccharin is illegal.According to the National Standard of China, the maximum permitted level is 8.189×10-4 mol·L-1 in food. In
WU Hao +4 more
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In order to get the information regarding the sweetener-water and sweetener-sweetener interactions, densities of sodium saccharin in water and (0.1, 0.3, and 0.5) m fructose have been measured at (298.15, 303.15, 308.15, and 313.15) K by the use of ...
Sanjeevan J. Kharat, Sachin M. Munde
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Habitual Preference for the Nondrug Reward in a Drug Choice Setting
For adaptive and efficient decision making, it must be possible to select between habitual alternative courses of action. However, research in rodents suggests that, even in the context of simple decision-making, choice behavior remains goal-directed. In
Youna Vandaele +4 more
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Noncaloric artificial sweeteners (NAS) are extensively introduced into commonly consumed drinks and foods worldwide. However, data on the health effects of NAS consumption remain elusive.
Zunji Shi +19 more
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Large-scale synthesis of the new saccharin-derived N-fluorosultam 1 is described, starting from readily available saccharin 2. A newly designed fluorination apparatus, which allows the preparation of 100-g quantities of 1 at atmospheric pressure, is ...
Kurt Auer +2 more
doaj +5 more sources
Sodium saccharin is intended to be used as a sweetener in feed and water for drinking for piglets, pigs for fattening and veal calves. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) considers the proposed maximum use level
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
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The electrodeposition of cobalt coatings is widely utilized in various industrial applications. Saccharin is commonly added as an organic additive to modify deposition quality, but its influence on coating properties is not yet fully understood.
Mohammad Alinezhadfar +5 more
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