Results 131 to 140 of about 496,628 (371)

Remote Control of Eukaryotic Gene Expression by a Modular Ultrasound‐Responsive RNA Toolkit

Angewandte Chemie International Edition, Accepted Article.
Achieving remote control of biological processes remains a significant challenge in genetics. Although ultrasound has been employed to remotely regulate biological functions by targeting mechanosensitive ion channels, existing systems are constrained by the limited responsiveness of specific channels to specific ultrasound frequencies and their ...
Andreas Herrmann, Fahimeh Charbgoo, Aman Ishaqat, Junlin Chen, Fabian Wiertz, Adrian Kuzmanović, Matthias Bartneck, Fabian Kiessling   +7 more
wiley   +1 more source

Relaxing the Hypotheses of Symmetry and Time-Reversibility in Genome Evolutionary Models [PDF]

British journal of mathematics and computer science. 5(4), 439-455 (2015), 2016
Various genome evolutionary models have been proposed these last decades to predict the evolution of a DNA sequence over time, essentially described using a mutation matrix. By essence, all of these models relate the evolution of DNA sequences to the computation of the successive powers of the mutation matrix.
arxiv  

Orphan proteins of unknown function in the mitochondrial intermembrane space proteome: new pathways and metabolic cross-talk [PDF]

, 2016
The mitochondrial intermembrane space (IMS) is involved in protein transport, lipid homeostasis and metal ion exchange, while further acting in signalling pathways such as apoptosis.
Manganas, Phanee, Nuebel, Esther, Tokatlidis, Konstantinos   +2 more
core   +1 more source

Transcriptomics data of 11 species of yeast identically grown in rich media and oxidative stress conditions

BMC Research Notes, 2019
Objective The objective of this experiment was to identify transcripts in baker’s yeast (Saccharomyces cerevisiae) that could have originated from previously non-coding genomic regions, or de novo.
William R. Blevins, Lucas B. Carey, M. Mar Albà   +2 more
doaj   +1 more source

Predicting the Evolution of Gene $ura3$ in the Yeast Saccharomyces Cerevisiae [PDF]

arXiv, 2017
Since the late `60s, various genome evolutionary models have been proposed to predict the evolution of a DNA sequence as the generations pass. Most of these models are based on nucleotides evolution, so they use a mutation matrix of size 4x4. They encompass for instance the well-known models of Jukes and Cantor, Kimura, and Tamura.
arxiv  

RGC1/RGC2 deletions cause increased sensitivity to oxidative stress in Saccharomyces cerevisiae, which can be overcome by constitutive nuclear Yap1 expression [PDF]

, 2016
Oxidative stress mechanism in yeast presents an innovative pathway to understand in creating the next generation of antifungal drugs. Rgc1 and Rgc2 are paralogous proteins that regulate the Fps1 glycerol channel in hyperosmotic stress.
Tsai, Michelle
core   +1 more source

The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]

, 2018
Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S, Gou, Liangke, Kruglyak, Leonid   +2 more
core   +1 more source

Greek Protected Designation of Origin Xinomavro Wines: A Deep Dive into Their Chemical Composition and Geographical Origin by Using Ultra High Performance Liquid Chromatography–Trapped Ion Mobility Spectrometry–Quadrupole Time of Flight–Mass Spectrometry

Analysis &Sensing, EarlyView.
Greek protected designation of origin Xinomavro wines are analyzed with ultra high performance liquid chromatography–trapped ion mobility spectrometry–quadrupole time of flight‐mass spectrometry (UHPLC‐TIMS‐QTOF‐MS). Both target and not‐target screening approaches are employed, leading to the identification and quantification of several polyphenols and
Panagiotis‐Loukas Gialouris, Eleni Nastou, Dafni Preza‐Mayo‐Kataki, Elli Goulioti, Yorgos Kotseridis, Nikolaos Thomaidis, Marilena Dasenaki   +6 more
wiley   +1 more source

Feruloyl oligosaccharides, isolated from bacterial fermented wheat bran, exhibit antioxidant effects in IPEC‐J2 cells and zebrafish model

Food Science &Nutrition, Volume 11, Issue 1, Page 295-306, January 2023., 2023
An excess of reactive oxygen species (ROS) can cause cell damage, and an accumulation of damage leads to cellular dysfunction resulting in a variety of diseases including abnormal aging, cancer, diabetes, and inflammation. In this study, feruloyl oligosaccharides (FOs) were obtained by solid‐state fermentation using wheat bran, and antioxidant activity
Qiuyan Chen, Jia Zhang, Yuan Wang, Ruifang Wang, Xiran Hao, Ruxin Wang, Yue Zheng, Xiaoping An, Jingwei Qi   +8 more
wiley   +1 more source

Morphology, cell division, and viability of Saccharomyces cerevisiae at high hydrostatic pressure [PDF]

arXiv, 2017
High hydrostatic pressure is commonly encountered in many environments, but the effects of high pressure on eukaryotic cells have been understudied. To understand the effects of hydrostatic pressure in the model eukaryote, Saccharomyces cerevisiae, we have performed quantitative experiments of cell division, cell morphology, and cell death under a wide
arxiv