Results 181 to 190 of about 496,628 (371)

Saccharomyces cerevisiae fungemia in a critically ill patient with acute cholangitis and long term probiotic use

open access: yesMedical Mycology Case Reports, 2019
Saccharomyces cerevisiae has recently been used as an ingredient in probiotic supplements. Invasive Saccharomyces infection have been documented, and multiple predisposing risk factors have been identified including critical illness, ICU admission ...
Mustafa Fadhel   +4 more
doaj  

Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae. [PDF]

open access: yes, 2019
Saccharomyces cerevisiae Srs2, in addition to its well-documented antirecombination activity, has been proposed to play a role in promoting synthesis-dependent strand annealing (SDSA).
Ede, Christopher   +8 more
core  

Characterization of the Cubamyces Menziesii Terpenome

open access: yesChemBioChem, EarlyView.
The genome of Cubamyces menziesii reveals 18 putative sesquiterpene cyclase genes. These genes are cloned and expressed in Escherichia coli, yielding 10 active enzymes. Using farnesyl diphosphate as substrate, the enzymes are analyzed, and the products characterized after bioconversion, uncovering diverse sesquiterpene structures. This study highlights
Létitia Leydet   +10 more
wiley   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, EarlyView.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Identification of Key Active‐Site Positions Controlling the Chemoselectivity of Aspergillus Brasiliensis Unspecific Peroxygenase

open access: yesChemBioChem, EarlyView.
Unspecific peroxygenase (UPO) from Aspergillus brasiliensis AbrUPO catalyzes the aromatic hydroxylation of substituted benzenes. By integrating structural elements from well‐characterized UPOs in AbrUPO variants, position 186 was identified as a critical determinant of enzyme chemoselectivity.
Fabian Schmitz   +8 more
wiley   +1 more source

Crystal structure of Methanococcus jannaschii dihydroorotase

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 91, Issue 1, Page 91-98, January 2023., 2023
Abstract In this paper, we report the structural analysis of dihydroorotase (DHOase) from the hyperthermophilic and barophilic archaeon Methanococcus jannaschii. DHOase catalyzes the reversible cyclization of N‐carbamoyl‐l‐aspartate to l‐dihydroorotate in the third step of de novo pyrimidine biosynthesis.
Jacqueline Vitali   +3 more
wiley   +1 more source

Anti-Cariogenic Effects of S. cerevisiae and S. boulardii in S. mutans–C. albicans Cross-Kingdom In Vitro Models

open access: yesPharmaceutics
Despite the well-documented health benefits of the probiotic Saccharomyces, its application in oral health has not been comprehensively assessed. Dental caries is a transmissible disease initiated by acid production of cariogenic bacteria and yeast, such
Dina Yousif   +8 more
doaj   +1 more source

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