Results 1 to 10 of about 6,084 (156)
The F204S mutation in adrenodoxin oxidoreductase drives salinomycin resistance in Eimeria tenella [PDF]
Veterinary ResearchSalinomycin is a polyether ionophore widely used for the treatment of coccidiosis in poultry. However, the emergence of coccidia strains resistant to salinomycin presents challenges for control efforts, and the mechanisms underlying this resistance in ...
Pei Sun +13 more
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Foods, 2023 The presence of antimicrobial residues in products of animal origin is a constant problem for consumer health. The aim of this study was to observe the effect of the addition of humic substances (H), fermented products (F) and a mixture of both (FH) to ...
Simona Hriciková +3 more
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Effects of salinomycin and ethanamizuril on the three microbial communities in vivo and in vitro
Frontiers in Microbiology, 2022 The fate of a drug is not only the process of drug metabolism in vivo and in vitro but also the homeostasis of drug-exposed microbial communities may be disturbed.
Xiaolei Cheng +6 more
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Anticancer Mechanisms of Salinomycin in Breast Cancer and Its Clinical Applications
Frontiers in Oncology, 2021 Breast cancer (BC) is the most frequent cancer among women worldwide and is the leading cause of cancer-related deaths in women. Cancer cells with stem cell-like features and tumor-initiating potential contribute to drug resistance, tumor recurrence, and
Hui Wang +7 more
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High-Resolution Electrospray and Ion Mobility Sequential Mass Spectrometry for Structural Characterisation of Anticancer Stem Cell Agent Salinomycin and Its Isomers [PDF]
MoleculesSalinomycin is a polyether ionophore natural product widely studied for its anticancer stem cell properties and well established anti-coccidial activity.
Candy Jiang, Paul J. Gates
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Animals, 2022 Unfavorable alterations of the commensal gut microbiota and dysbacteriosis is a major health problem in the poultry industry. Understanding how dietary intervention alters the microbial ecology of broiler chickens is important for prevention strategies ...
Mohammad Naghizadeh +5 more
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Frontiers in Bioengineering and Biotechnology, 2019 Salinomycin, an important polyketide, has been widely utilized in agriculture to inhibit growth of pathogenic bacteria. In addition, salinomycin has great potential in treatment of cancer cells.
Kuipu Zhang +2 more
exaly +3 more sources
Chloroquine inhibits salinomycin-induced autophagy for collaborative anticancer effect in breast cancer [PDF]
BioImpactsIntroduction: Breast cancer (BC) presents significant morbidity and mortality challenges. Autophagy plays a contradictory role in BC. The chemotherapeutic agent salinomycin exhibits anticancer effects, but its effectiveness is limited by over-activation ...
Xiaoting Yang +3 more
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FoodsSalinomycin is a coccidiostat approved as a feed additive for the prevention of coccidiosis in poultry. Official control of its residues is set by the Commission Delegated Regulation (EU) 2022/1644.
Daniela Spišáková +3 more
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In Vitro Antiviral Activities of Salinomycin on Porcine Epidemic Diarrhea Virus
Viruses, 2021 Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus, has catastrophic impacts on the global pig industry. Owing to the lack of effective vaccines and specific therapeutic options for PEDV, it is pertinent to develop new and available ...
Chen Yuan +6 more
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