Results 181 to 190 of about 7,383 (256)

An antibiotic that mediates immune destruction of senescent cancer cells. [PDF]

Proc Natl Acad Sci U S A
Casagrande Raffi G, Chen J, Feng X, Chen Z, Lieftink C, Deng S, Mo J, Zeng C, Steur M, Wang J, Bleijerveld OB, Hoekman L, van der Wel N, Wang F, Beijersbergen R, Zheng J, Bernards R, Wang L.   +17 more
europepmc   +1 more source

Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer. [PDF]

EMBO J
Nehme J, Maassen S, Bravaccini S, Zanoni M, Gianni C, De Giorgi U, Soto-Gamez A, Altulea A, Gheorghe T, Wang B, Demaria M.   +10 more
europepmc   +1 more source

Low-Dose Salinomycin Alters Mitochondrial Function and Reprograms Global Metabolism in Burkitt Lymphoma. [PDF]

Int J Mol Sci
Zdanowicz A, Ilchenko O, Ciechanowicz A, Chi H, Struga M, Pyrzynska B.   +5 more
europepmc   +1 more source

Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan. [PDF]

Medicines (Basel)
Fahey JW, Liu H.
europepmc   +1 more source

The effect of chemotherapeutic agents on epidermal neural crest stem cells. [PDF]

Mol Biol Res Commun
Rahmani-Kukia N, Keshavarzi F, Salehi MS, Bozorg-Ghalati F, Mojtahedi Z, Zamani M, Azarpira N, Mokarram P.   +7 more
europepmc   +1 more source

Development of an immunochromatography assay for salinomycin and methyl salinomycin in honey [PDF]

Food and Agricultural Immunology, 2019
This study developed a sensitive monoclonal antibody, 3A3, to salinomycin (SLM) and methyl salinomycin (MLN). The monoclonal antibody 3A3 is highly specific for SLM with an antibody halfinhibitory concentration (IC 50) of 0.86 ng/mL, a detection limit of 0.28 ng/mL, and a linear detection range of 0.28–2.26 ng/mL.
Chuanlai Xu, Liqiang Liu, Xiaoling Wu
exaly   +3 more sources

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Development of an ELISA for salinomycin and depletion kinetics of salinomycin residues in poultry

Food Additives and Contaminants, 1995
Salinomycin is widely used as a feed additive to control coccidiosis in the broiler industry world-wide. EC legislation on veterinary drug residues will soon be extended to cover poultry. This will require the development of rapid assays to screen for the presence of residual concentrations of this and other drugs in poultry meat.
D Glenn Kennedy, W John Blanchflower
exaly   +3 more sources

Polylactic Acid Based Biodegradable Hybrid Block Copolymeric Nanoparticle Mediated Co-delivery of Salinomycin and Doxorubicin for Cancer Therapy.

International journal of pharmaceutics, 2023
Existence of cancer stem cells (CSCs) are primarily responsible for chemoresistance, cancer reoccurrence and treatment failure in cancer patients. Eliminating CSCs along with bulk tumor is a necessity to achieve complete cancer inhibition.
M. Anees, N. Mehrotra, Sachchidanand Tiwari, Dinesh Kumar, S. Kharbanda, Harpal Singh   +5 more
semanticscholar   +1 more source

Potent salinomycin C20-O-alkyl oxime derivative SAL-98 efficiently inhibits tumor growth and metastasis by affecting Wnt/β-catenin signal pathway.

Biochemical Pharmacology, 2023
The dysregulation of Wnt/β-catenin signaling pathway is closely related to tumorigenesis, metastasis and cancer stem cell maintenance. Salinomycin is a polyether ionophore antibiotic that selectively eliminates cancer stem cells by inhibiting the Wnt/β ...
Lei Tang, Wenfang Duan, Chi Zhang, Yulu Shi, Wen-bin Tu, Kangfan Lei, Wenxuan Zhang, Song Wu, Jihong Zhang   +8 more
semanticscholar   +1 more source

Salinomycin poisoning in horses

Veterinary Record, 1987
Six cases of accidental salinomycin poisoning in horses are described. The horses were fed a contaminated ration and presented clinical signs which were extremely varied in nature and severity. However, the range of signs, including anorexia, colic, weakness and ataxia bore similarities to those described in horses poisoned with the related ionophore ...
J, Rollinson, F G, Taylor, J, Chesney
openaire   +2 more sources