Optical kicking of liquid droplets for sample delivery in ultrafast soft X-ray experiments. [PDF]
J Synchrotron RadiatWe present a technique based on the optical force of a femtosecond laser acting on liquid micro-droplets for their precise manipulation in a vacuum, enabling an efficient sample delivery system for soft X-ray experiments. Conventional liquid jet methods,
Ebrahimpour Z +3 more
europepmc +2 more sources
Picosecond infrared laser driven sample delivery for simultaneous liquid-phase and gas-phase electron diffraction studies. [PDF]
Struct Dyn, 2022 Here, we report on a new approach based on laser driven molecular beams that provides simultaneously nanoscale liquid droplets and gas-phase sample delivery for femtosecond electron diffraction studies.
Huang Z +3 more
europepmc +2 more sources
Sample delivery methods for protein X-ray crystallography with a special focus on sample consumption. [PDF]
Nat CommunSerial crystallography (SX) has revolutionized structural biology by enabling high-resolution structure determination for important classes of proteins, including the study of relevant biomolecular reaction mechanisms.
Manna A +4 more
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Transdermal microconduits by microscission for drug delivery and sample acquisition [PDF]
BMC Medicine, 2004 Background Painless, rapid, controlled, minimally invasive molecular transport across human skin for drug delivery and analyte acquisition is of widespread interest.
Anderson R +4 more
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Mixing and jetting analysis using continuous flow microfluidic sample delivery devices. [PDF]
RSC Adv, 2020 Design schematics of microfluidic mix- and-jet devices for serial femtosecond crystallography (SFX) at X-ray free electron lasers (XFELs).
Hejazian M +3 more
europepmc +4 more sources
Helium-electrospray improves sample delivery in X-ray single-particle imaging experiments. [PDF]
Sci RepImaging the structure and observing the dynamics of isolated proteins using single-particle X-ray diffractive imaging (SPI) is one of the potential applications of X-ray free-electron lasers (XFELs).
Yenupuri TV +6 more
europepmc +2 more sources
Microfluidics at Fiber Tip for Nanoliter Delivery and Sampling [PDF]
Advanced Science, 2021 AbstractDelivery and sampling nanoliter volumes of liquid can benefit new invasive surgical procedures. However, the dead volume and difficulty in generating constant pressure flow limits the use of small tubes such as capillaries. This work demonstrates sub‐millimeter microfluidic chips assembled directly on the tip of a bundle of two hydrophobic ...
Antoine Barbot +3 more
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IUCrJ, 2023 In this commentary, we explore the pioneering implementation of 3D-printed thin liquid sheet devices for advanced X-ray scattering and spectroscopy experiments at high-repetition rate XFELs.
Martin Trebbin
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Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX
IUCrJ, 2022 CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan +11 more
doaj +1 more source
A stop-flow sample delivery system for transient spectroscopy [PDF]
Review of Scientific Instruments, 2021 A stop-flow sample delivery system for transient spectroscopy is presented, which is, in particular, suited for laser-based instruments (quantum-cascade lasers or amplified femtosecond lasers) with excitation pulse repetition rates in the range 10–100 Hz.
Buhrke, David +3 more
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