Results 31 to 40 of about 13,205,348 (309)

Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX

IUCrJ, 2022
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers.
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato   +11 more
doaj   +1 more source

A Numerical Study of Sub-Millisecond Integrated Mix-and-Inject Microfluidic Devices for Sample Delivery at Synchrotron and XFELs

Applied Sciences, 2021
Microfluidic devices which integrate both rapid mixing and liquid jetting for sample delivery are an emerging solution for studying molecular dynamics via X-ray diffraction.
Majid Hejazian, E. Balaur, B. Abbey
semanticscholar   +1 more source

Preventing Bio-Bloopers and XFEL Follies: Best Practices from your Friendly Instrument Staff

Crystals, 2020
Serial Femtosecond Crystallography (SFX) at X-ray Free electron Lasers (XFELs) is a relatively new field promising to deliver unparalleled spatial and temporal resolution on biological systems and there dynamics.
Christopher Kupitz, Raymond G. Sierra
doaj   +1 more source

Radiation Damage of Polydimethylsiloxane and Polyimide by X-ray Free-Electron Laser

Applied Sciences, 2022
A crystal delivery system is essential in serial femtosecond crystallography experiments using an X-ray free-electron laser (XFEL). Investigating the XFEL-induced radiation damage to materials potentially applicable to sample delivery devices is vital ...
Keondo Lee, Donghyeon Lee, Sangwon Baek, Jihan Kim, Jaehyun Park, Sang Jae Lee, Sehan Park, Jangwoo Kim, Jong-Lam Lee, Wan Kyun Chung, Yunje Cho, Ki Hyun Nam   +11 more
doaj   +1 more source

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

IUCrJ, 2022
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules.
Kara A Zielinski, Andreas Prester, Hina Andaleeb, Soi Bui, Oleksandr Yefanov, Lucrezia Catapano, Alessandra Henkel, Max O. Wiedorn, Olga Lorbeer, Eva Crosas, Jan Meyer, Valerio Mariani, Martin Domaracky, Thomas A. White, Holger Fleckenstein, Iosifina Sarrou, Nadine Werner, Christian Betzel, Holger Rohde, Martin Aepfelbacher, Henry N. Chapman, Markus Perbandt, Roberto A. Steiner, Dominik Oberthuer   +23 more
doaj   +1 more source

Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs

IUCrJ, 2023
Fixed targets are a popular form of sample-delivery system used in serial crystallography at synchrotron and X-ray free-electron laser sources. They offer a wide range of sample-preparation options and are generally easy to use.
Melissa Carrillo, Thomas J. Mason, Agnieszka Karpik, Isabelle Martiel, Michal W. Kepa, Katherine E. McAuley, John H. Beale, Celestino Padeste   +7 more
doaj   +1 more source

Approach of Serial Crystallography

Crystals, 2020
Radiation damage and cryogenic sample environment are an experimental limitation observed in the traditional X-ray crystallography technique. However, the serial crystallography (SX) technique not only helps to determine structures at room temperature ...
Ki Hyun Nam
doaj   +1 more source

Lymphatic Cannulation for Lymph Sampling and Molecular Delivery [PDF]

The Journal of Immunology, 2019
Abstract Unlike the blood, the interstitial fluid and the deriving lymph are directly bathing the cellular layer of each organ. As such, composition analysis of the lymphatic fluid can provide more precise biochemical and cellular information on an organ's health and be a valuable resource for biomarker discovery.
David C Zawieja, Sangeetha Thangaswamy, Wei Wang, Raquel Furtado, Cristina C Clement, Zachary Papadopoulos, Marco Vigano, Eric A Bridenbaugh, Lello Zolla, Anatoliy A Gashev, Jonathan Kipnis, Gregoire Lauvau, Laura Santambrogio   +12 more
openaire   +2 more sources

Computational simulation of the effects of interfacial tension in microfluidic flow focusing droplet generators

Frontiers in Physics, 2023
We present simulations of a square flow focusing droplet generator device exploring its performance characteristics over a range of interfacial surface tension values and varying neck width.
Matthew Stevens, Eugeniu Balaur, Brian Abbey   +2 more
doaj   +1 more source

Potential of Time-Resolved Serial Femtosecond Crystallography Using High Repetition Rate XFEL Sources

Applied Sciences, 2022
This perspective review describes emerging techniques and future opportunities for time-resolved serial femtosecond crystallography (TR-SFX) experiments using high repetition rate XFEL sources.
Raphaël de Wijn, Diogo V. M. Melo, Faisal H. M. Koua, Adrian P. Mancuso   +3 more
doaj   +1 more source