Results 21 to 30 of about 878,005 (252)

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

open access: yesIUCrJ, 2022
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules.
Kara A Zielinski   +23 more
doaj   +1 more source

A stop-flow sample delivery system for transient spectroscopy [PDF]

open access: yesReview of Scientific Instruments, 2021
A stop-flow sample delivery system for transient spectroscopy is presented, which is, in particular, suited for laser-based instruments (quantum-cascade lasers or amplified femtosecond lasers) with excitation pulse repetition rates in the range 10–100 Hz.
Buhrke, David   +3 more
openaire   +3 more sources

Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs

open access: yesIUCrJ, 2023
Fixed targets are a popular form of sample-delivery system used in serial crystallography at synchrotron and X-ray free-electron laser sources. They offer a wide range of sample-preparation options and are generally easy to use.
Melissa Carrillo   +7 more
doaj   +1 more source

Approach of Serial Crystallography

open access: yesCrystals, 2020
Radiation damage and cryogenic sample environment are an experimental limitation observed in the traditional X-ray crystallography technique. However, the serial crystallography (SX) technique not only helps to determine structures at room temperature ...
Ki Hyun Nam
doaj   +1 more source

Computational simulation of the effects of interfacial tension in microfluidic flow focusing droplet generators

open access: yesFrontiers in Physics, 2023
We present simulations of a square flow focusing droplet generator device exploring its performance characteristics over a range of interfacial surface tension values and varying neck width.
Matthew Stevens   +2 more
doaj   +1 more source

Lymphatic Cannulation for Lymph Sampling and Molecular Delivery [PDF]

open access: yesThe Journal of Immunology, 2019
Abstract Unlike the blood, the interstitial fluid and the deriving lymph are directly bathing the cellular layer of each organ. As such, composition analysis of the lymphatic fluid can provide more precise biochemical and cellular information on an organ's health and be a valuable resource for biomarker discovery.
David C Zawieja   +12 more
openaire   +2 more sources

Sample Delivery Systems for Serial Femtosecond Crystallography at the PAL-XFEL

open access: yesPhotonics, 2023
Serial femtosecond crystallography (SFX) using an X-ray free electron laser (XFEL) enables the determination of room-temperature structures without causing radiation damage.
Jaehyun Park, Ki Hyun Nam
doaj   +1 more source

A guide to sample delivery systems for serial crystallography [PDF]

open access: yesThe FEBS Journal, 2019
Crystallography has made a notable contribution to our knowledge of structural biology. For traditional crystallography experiments, the growth of crystals with large size and high quality is crucial, and it remains one of the bottlenecks. In recent years, the successful application of serial femtosecond crystallography (SFX) provides a new choice when
Feng‐Zhu Zhao   +6 more
openaire   +2 more sources

Potential of Time-Resolved Serial Femtosecond Crystallography Using High Repetition Rate XFEL Sources

open access: yesApplied Sciences, 2022
This perspective review describes emerging techniques and future opportunities for time-resolved serial femtosecond crystallography (TR-SFX) experiments using high repetition rate XFEL sources.
Raphaël de Wijn   +3 more
doaj   +1 more source

Mass Transport Effects in Suspended Waveguide Biosensors Integrated in Microfluidic Channels

open access: yesSensors, 2012
Label-free optical biosensors based on integrated photonic devices have demonstrated sensitive and selective detection of biological analytes. Integrating these sensor platforms into microfluidic devices reduces the required sample volume and enables ...
Andrea M. Armani, Chaitanya R. Murthy
doaj   +1 more source

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