Results 21 to 30 of about 878,005 (252)
Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules.
Kara A Zielinski +23 more
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A stop-flow sample delivery system for transient spectroscopy [PDF]
A stop-flow sample delivery system for transient spectroscopy is presented, which is, in particular, suited for laser-based instruments (quantum-cascade lasers or amplified femtosecond lasers) with excitation pulse repetition rates in the range 10–100 Hz.
Buhrke, David +3 more
openaire +3 more sources
Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs
Fixed targets are a popular form of sample-delivery system used in serial crystallography at synchrotron and X-ray free-electron laser sources. They offer a wide range of sample-preparation options and are generally easy to use.
Melissa Carrillo +7 more
doaj +1 more source
Approach of Serial Crystallography
Radiation damage and cryogenic sample environment are an experimental limitation observed in the traditional X-ray crystallography technique. However, the serial crystallography (SX) technique not only helps to determine structures at room temperature ...
Ki Hyun Nam
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We present simulations of a square flow focusing droplet generator device exploring its performance characteristics over a range of interfacial surface tension values and varying neck width.
Matthew Stevens +2 more
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Lymphatic Cannulation for Lymph Sampling and Molecular Delivery [PDF]
Abstract Unlike the blood, the interstitial fluid and the deriving lymph are directly bathing the cellular layer of each organ. As such, composition analysis of the lymphatic fluid can provide more precise biochemical and cellular information on an organ's health and be a valuable resource for biomarker discovery.
David C Zawieja +12 more
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Sample Delivery Systems for Serial Femtosecond Crystallography at the PAL-XFEL
Serial femtosecond crystallography (SFX) using an X-ray free electron laser (XFEL) enables the determination of room-temperature structures without causing radiation damage.
Jaehyun Park, Ki Hyun Nam
doaj +1 more source
A guide to sample delivery systems for serial crystallography [PDF]
Crystallography has made a notable contribution to our knowledge of structural biology. For traditional crystallography experiments, the growth of crystals with large size and high quality is crucial, and it remains one of the bottlenecks. In recent years, the successful application of serial femtosecond crystallography (SFX) provides a new choice when
Feng‐Zhu Zhao +6 more
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This perspective review describes emerging techniques and future opportunities for time-resolved serial femtosecond crystallography (TR-SFX) experiments using high repetition rate XFEL sources.
Raphaël de Wijn +3 more
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Mass Transport Effects in Suspended Waveguide Biosensors Integrated in Microfluidic Channels
Label-free optical biosensors based on integrated photonic devices have demonstrated sensitive and selective detection of biological analytes. Integrating these sensor platforms into microfluidic devices reduces the required sample volume and enables ...
Andrea M. Armani, Chaitanya R. Murthy
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