Results 21 to 30 of about 2,171,365 (292)

Preventing Bio-Bloopers and XFEL Follies: Best Practices from your Friendly Instrument Staff

open access: yesCrystals, 2020
Serial Femtosecond Crystallography (SFX) at X-ray Free electron Lasers (XFELs) is a relatively new field promising to deliver unparalleled spatial and temporal resolution on biological systems and there dynamics.
Christopher Kupitz, Raymond G. Sierra
doaj   +1 more source

Radiation Damage of Polydimethylsiloxane and Polyimide by X-ray Free-Electron Laser

open access: yesApplied Sciences, 2022
A crystal delivery system is essential in serial femtosecond crystallography experiments using an X-ray free-electron laser (XFEL). Investigating the XFEL-induced radiation damage to materials potentially applicable to sample delivery devices is vital ...
Keondo Lee   +11 more
doaj   +1 more source

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

open access: yesIUCrJ, 2022
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules.
Kara A Zielinski   +23 more
doaj   +1 more source

Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs

open access: yesIUCrJ, 2023
Fixed targets are a popular form of sample-delivery system used in serial crystallography at synchrotron and X-ray free-electron laser sources. They offer a wide range of sample-preparation options and are generally easy to use.
Melissa Carrillo   +7 more
doaj   +1 more source

Approach of Serial Crystallography

open access: yesCrystals, 2020
Radiation damage and cryogenic sample environment are an experimental limitation observed in the traditional X-ray crystallography technique. However, the serial crystallography (SX) technique not only helps to determine structures at room temperature ...
Ki Hyun Nam
doaj   +1 more source

Computational simulation of the effects of interfacial tension in microfluidic flow focusing droplet generators

open access: yesFrontiers in Physics, 2023
We present simulations of a square flow focusing droplet generator device exploring its performance characteristics over a range of interfacial surface tension values and varying neck width.
Matthew Stevens   +2 more
doaj   +1 more source

Sample Delivery Systems for Serial Femtosecond Crystallography at the PAL-XFEL

open access: yesPhotonics, 2023
Serial femtosecond crystallography (SFX) using an X-ray free electron laser (XFEL) enables the determination of room-temperature structures without causing radiation damage.
Jaehyun Park, Ki Hyun Nam
doaj   +1 more source

Lymphatic Cannulation for Lymph Sampling and Molecular Delivery [PDF]

open access: yesThe Journal of Immunology, 2019
Abstract Unlike the blood, the interstitial fluid and the deriving lymph are directly bathing the cellular layer of each organ. As such, composition analysis of the lymphatic fluid can provide more precise biochemical and cellular information on an organ's health and be a valuable resource for biomarker discovery.
David C Zawieja   +12 more
openaire   +2 more sources

Potential of Time-Resolved Serial Femtosecond Crystallography Using High Repetition Rate XFEL Sources

open access: yesApplied Sciences, 2022
This perspective review describes emerging techniques and future opportunities for time-resolved serial femtosecond crystallography (TR-SFX) experiments using high repetition rate XFEL sources.
RaphaĆ«l de Wijn   +3 more
doaj   +1 more source

Variations in the hospital management of self harm in adults in England: observational study [PDF]

open access: yes, 2004
More than 140 000 people present to hospital after an episode of self harm each year in England and Wales. Improving the general hospital management of these people is a key area in preventing suicide. Although professional consensus has been reached
Bennewith, O.   +4 more
core   +2 more sources

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