Results 201 to 210 of about 539,723 (262)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A dataset on habitat-associated changes in the fecal microbiota of Drosophila melanogaster. [PDF]

Sci Data
Riedel EK, Rohlfs M.
europepmc   +1 more source

Multirate sampled-data controllers

, 1990
openaire   +1 more source

Public health significance of prevalence and risk factors associated with Toxoplasma gondii infection in goats sampled from two quarantine facilities and an institutional farm in Maiduguri metropolis, Borno state, Nigeria. [PDF]

Sci Rep
Muhammad AS, Kudi AC, Mohammed A, Kia GSN, Adamu SG, Musa HI, Tijjani AO, Mohammed S, Saidu AS, Bukar MM, Bukar-Kolo YM.   +10 more
europepmc   +1 more source

Aerosol-Generating Potential of Topical Nasal Preparation Before Nasoendoscopy: A Quantitative Study. [PDF]

Laryngoscope Investig Otolaryngol
Chua AJ, Yu Y, Zhang EZ, Tan VY, Luhung I, Schuster SC, Sng A, Sadovoy AV.   +7 more
europepmc   +1 more source

Acute Cytokine Responses to High-Intensity Intermittent Exercise in Humans: A Systematic Review. [PDF]

Int J Mol Sci
Trybulski R, Bjelica D, Çitozi R, Kisilewicz A, Smoter M, Urban J.   +5 more
europepmc   +1 more source

Invaders taking over-Mollusc faunal change in volcanic barrier lakes of the Albertine Rift biodiversity hotspot. [PDF]

PLoS One
Ssenkuba F, Rwibutso M, Dusabe MC, Tumusiime J, Albrecht C.   +4 more
europepmc   +1 more source