Results 201 to 210 of about 30,989,817 (290)

Seroprevalence and Factors Associated with <i>Toxoplasma gondii</i> Seropositivity in Small Ruminants in Northeastern Portugal. [PDF]

Animals (Basel)
Pereira T, Rodrigues C, Caldeira MJ, Teixeira Rodrigues F, Jacob-Ferreira J, Lopes AP, Quintas H.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Hybrid Intrusion Detection System with Real-Time Concept Drift Detection for Enhanced IoT Security. [PDF]

Sensors (Basel)
Obaidat MA, Abouali M, Shakeel A.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Computational blueprint and stereochemical validation of a small peptide derived from <i>Lacticaseibacillus casei</i> VITCM05 targeting estrogen receptor alpha and human epidermal growth factor receptor 2. [PDF]

Front Bioinform
Shree Kumari GR, Vaithilingam M.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Seasonal Nile Crocodile Damage to Fishing Gear, Incident Reporting and Livelihood Responses in the Sudd Wetlands, South Sudan. [PDF]

Animals (Basel)
Benansio JS, Damaya GS, Okorie IE, Nadarajah S.   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Subunit-dependent interfacial assembly of wheat gliadin subunits by <i>Lycium barbarum</i> polysaccharide underlies foam stabilization. [PDF]

Food Chem X
Li C, Wang B, Yu HY, Dai XL, Yang T.
europepmc   +1 more source