Results 171 to 180 of about 914,102 (311)

DEPTH-BASED CLASSIFICATION FOR FUNCTIONAL DATA [PDF]

Classification is an important task when data are curves. Recently, the notion of statistical depth has been extended to deal with functional observations.
Juan Romo, Sara Lopez-Pintado
core  

Data on the margins \u2013 Data from LGBTIQ+ Populations in European Social Science Data Archives

A first step towards identifying and closing data gaps is to take stock of data that already exists. For this dataset, we collected LGBTIQ+ data in European social science archives.
Recker, Jonas, GESIS - Leibniz-Institut f\ufcr Sozialwissenschaften, Perry, Anja, GESIS - Leibniz-Institut f\ufcr Sozialwissenschaften   +1 more
core   +1 more source

Learning from irregularly sampled data for endomicroscopy super-resolution: a comparative study of sparse and dense approaches. [PDF]

Int J Comput Assist Radiol Surg, 2020
Szczotka AB, Shakir DI, Ravì D, Clarkson MJ, Pereira SP, Vercauteren T.   +5 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Robust sampled data control

, 1990
Cataloged from PDF version of article.Includes bibliographical references leaves 39-40.Robust control of uncertain plants is a major area of interest in control theory.
Ocalı, Ogan
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

LQ-control of sampled continuous-time systems

Control Systems;controle ...
Willigenburg, L.G. van, Engwerda, J.C.
core  

Sampled-data fuzzy [Formula: see text] estimators for control of nonlinear parabolic partial differential equations. [PDF]

Sci Rep
Sivakumar M, Dharani S, Cao J.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source