Results 191 to 200 of about 914,102 (311)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Data repository for sample data

open access: yes
Patient data and analyses results will be handled by ITTM. The ZeBanC will store the samples with the corresponding data. For data storage, the LIMS system CentraXX is used. Both ITTM and the ZeBanC will coordinate data transfer or rather data linkage.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Sampled-data H∞ filtering of Takagi–Sugeno fuzzy systems with interval time-varying delays

open access: yes, 2014
The sampled-data H∞ filtering for a continuous-time Takagi–Sugeno fuzzy system with an interval time varying state delay is investigated, where the measurement outputs from the plant to the filter are assumed to be sampled at discrete instants with a ...
Jiang, Xiefu.   +5 more
core  

System Identification Algorithm for Non-Uniformly Sampled Data. [PDF]

open access: yesIFAC Pap OnLine, 2017
Bekiroglu K   +3 more
europepmc   +1 more source

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