Plant-Based Therapeutics Against Communicable Diseases: A Review of Ethnopharmacology and Medicinal Chemistry Approaches. [PDF]
Pathak M +4 more
europepmc +1 more source
Effects of Combined Oregano Essential Oil and <i>Macleaya cordata</i> Extract on Growth, Antioxidant Capacity, Immune Function, and Fecal Microbiota in Broilers. [PDF]
Lu Y +13 more
europepmc +1 more source
Transcriptomic and metabolomic analysis of the antibacterial mechanism of sanguinarine against Enterobacter cloacae in vitro. [PDF]
Yang T, Sha H, Bi W, Zeng J, Su D.
europepmc +1 more source
<i>Macleaya cordata</i> Alkaloids Sanguinarine and Chelerythrine Inhibit <i>Nocardia seriolae</i> by Disrupting Cell Envelope Integrity and Energy Metabolism: Insights from Transcriptomic Analysis. [PDF]
Huang L +9 more
europepmc +1 more source
Anticancer Perspectives of Sanguinarine: A Review
Background: Sanguinarine, a benzophenanthridine alkaloid extracted from Sanguinaria canadensis has been found to show an inhibitory role on proapoptotic and growth inhibitory activities in various tumor cells of experimental subjects. Objective: This review highlights and summarizes the effects of sanguinarine against cancers alongside the possible ...
Syed Amir Gilani +5 more
openaire +2 more sources
Structure of Sanguinarine Base
The structure of sanguinarine free base was examined. The base is either bis[6-(5,6-dihydrosanguinarinyl)] ether (3) or bis[6-(5,6-dihydrosanguinarinyl)]amine (4) depending on whether Na2CO3 or NH3, respectively, is used as an alkalizing agent.
Jiří Dostál +6 more
openaire +2 more sources
Suppression of angiogenesis by the plant alkaloid, sanguinarine
Sanguinarine is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadensis. Its principal pharmacologic use is in dental products where it has antibacterial, antifungal, and anti-inflammatory activities that reduce gingival inflammation and supragingival plaque formation.
Eun, JP, Koh, GY Koh, Gou Young
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The Anticancer Effect of Sanguinarine: A Review
Current Pharmaceutical Design, 2018In vitro and in vivo studies have revealed that Sanguinarine has antioxidant, anti-inflammatory, proapoptotic, and growth inhibitory effects on tumor cells of a variety of cancers. Previous research showed that sanguinarine induced apoptosis (cell death) and/or antiproliferative while reducing tumor cell antiangiogenic and anti-invasive properties ...
Guiping Guan
exaly +3 more sources
Disposition of sanguinarine in the rat
Xenobiotica, 2007Sanguinarine is an alkaloid with known antibiotic and anti-inflammatory activity and its pharmacokinetics have been studied in the rat after a single oral dose (10 mg kg(-1) body weight). Alkaloid determination in the plasma and liver was carried out by high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC/ESI-MS).
Marie Stiborova +2 more
exaly +3 more sources
Comparative antiplaque activity of sanguinarine and chlorhexidine in man
Abstract This clinical investigation examined the effect of a sanguinarine extract on bacterial plaque growth in man. Three different mouthrinses were examined: (i) Veadent® containing 0.03% sanguinarine and 0.2% zinc chloride (test rinse); (ii) a vehicle solution containing all the excipients of Veadent® except the 0.03% sanguinarine (control rinse); (
M, Quirynen +2 more
openaire +3 more sources

