Results 51 to 60 of about 105,044 (309)

Effects of a saponin fraction extracted from Trigonella foenum-graecum L. and two commercially available saponins on sex ratio and gonad histology of Nile tilapa fry, Oreochromis niloticus (L.) [PDF]

, 2013
Over three million tonnes (t) of tilapia, mostly Nile tilapia (Oreochromis niloticus, L.), are produced annually making it the second most abundantly produced freshwater fish (FAO, 2010).
Abu-Lafi, S., Becker, K., Dweik, H., Focken, U., Francis, G., Kerem, Z., Levavi-Sivan, B., Qutob, M., Stadtlander, T.   +8 more
core  

Studies on saponin production in tropical medicinal plants Maesa argentea and Maesa lanceolata [PDF]

, 2015
The continuous need for new compounds with important medicinal activities has lead to the identification and characterization of various plant-derived natural products.
Faizal, Ahmad, Geelen, Danny
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Anti-SARS-CoV-2 Activity of Ampelozizyphus amazonicus (Saracura-Mirá): Focus on the Modulation of the Spike-ACE2 Interaction by Chemically Characterized Bark Extracts by LC-DAD-APCI-MS/MS

Molecules, 2023
Traditional medicine shows several treatment protocols for COVID-19 based on natural products, revealing its potential as a possible source of anti-SARS-CoV-2 agents.
Mariana Freire Campos, Simony Carvalho Mendonça, Evelyn Maribel Condori Peñaloza, Beatriz A. C. de Oliveira, Alice S. Rosa, Gilda Guimarães Leitão, Amanda R. Tucci, Vivian Neuza S. Ferreira, Thamara Kelcya F. Oliveira, Milene Dias Miranda, Diego Allonso, Suzana Guimarães Leitão   +11 more
doaj   +1 more source

Diets containing sea cucumber (Isostichopus badionotus) meals are hypocholesterolemic in young rats [PDF]

, 2013
Peer reviewedPublisher ...
A Venkateswaran, Alberto Davalos, AO Odegaard, AS Greenberg, AV Khera, BA Janowski, C Zetina Moguel, CD Mathers, DE Kleiner, DJ Gordon, DP Mertz, ER Mojica, FR Van der Leij, G Grant, George Grant, GJ Miller, H Komano, H Leontowicz, HA Tyroler, HH Liu, Hirian Alonso Moshe Barrera-Perez, I Hawa, J Ayo, J Folch, J Lin, J Wen, JC Cohen, JC Cohen, JC Yoon, JD Horton, Jean-Marc A Lobaccaro, JJ Repa, Jorge Montero, Jorge Rubio-Piña, JR Schultz, JW Heinecke, JY Chiang, K Liu, KJ Livak, L Olivera, Leticia Olivera-Castillo, M Yahyavi, MC Damiani, MD Säemann, ME Rodríguez, MF Lopes-Virella, Miguel Angel Olvera-Novoa, N Hasegawa, N Torres, NE Miller, Nina Valadez-Gonzalez, P Araujo, P Lefebvre, Pablo Acereto-Escoffie, RG Herrmann, RK Semple, Roche Diagnostics, Rossanna Rodriguez-Canul, RR Sokal, S Acton, S Najwa, T Park, T Rajamohan, T Sugawara, VL Roger, Víctor Ceja-Moreno, X Duan, X Hu, XQ Hu, XQ Hu, Y Zhong, Yasser Chim-Chi, Z Hossain   +72 more
core   +4 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Regulation of anti-tumour effects of Paris polyphylla saponins via ROS: molecular mechanisms and therapeutic potentials

Frontiers in Pharmacology
Reactive oxygen species (ROS) exhibit a dual regulatory role in cancer biology. While moderate ROS levels promote tumorigenesis via DNA mutagenesis, excessive ROS accumulation induces cancer cell death through oxidative stress. Therefore, ROS homeostasis
Jia Liu, Yongping Mu, Yongping Mu, Ke Qi, Jiayi Li, Yang Hu   +5 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The effect of saponins from Ampelozizyphus amazonicus Ducke on the renal Na⁺ pumps’ activities and urinary excretion of natriuretic peptides

BMC Complementary and Alternative Medicine, 2012
Background In a previous study, we showed that a saponin mixture isolated from the roots of Ampelozizyphus amazonicus Ducke (SAPAaD) reduces urine excretion in rats that were given an oral loading of 0.9 % NaCl (4 ml/100 g body weight).
Diniz Lúcio Ricardo, Portella Viviane, Cardoso Flávia, de Souza Aloa, Caruso-Neves Celso, Cassali Geovanni, dos Reis Adelina, Brandão MariadasGraçasLins, Vieira Maria Aparecida   +8 more
doaj   +1 more source

Potential Use of Agave Genus in Neuroinflammation Management

Plants, 2022
Agavaceae contains about 480 species, commonly used in the production of alcoholic beverages such as tequila and mezcal, making it a resource of economic and cultural importance.
Maribel Herrera-Ruiz, Enrique Jiménez-Ferrer, Manasés González-Cortazar, Alejandro Zamilpa, Alexandre Cardoso-Taketa, Martha Lucía Arenas-Ocampo, Antonio Ruperto Jiménez-Aparicio, Nayeli Monterrosas-Brisson   +7 more
doaj   +1 more source