Results 131 to 140 of about 1,124 (173)
The Lipid Composition of the Exo-Metabolome from <i>Haemonchus contortus</i>. [PDF]
MetabolitesGodoy P +4 more
europepmc +1 more source
Contrasting Effects of Clozapine and Risperidone on Cholesterol Metabolism, Synaptic Proteins, and Transcriptional Regulation in Human LUHMES Neurons. [PDF]
Mol NeurobiolRybczyński P +7 more
europepmc +1 more source
Crystal structures of saposins A and C [PDF]
Protein Science, 2006 AbstractSaposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. The saposins interact with lipids, leading to an enhanced accessibility of the lipid headgroups to their cognate hydrolases.
Gilbert G Privé
exaly +4 more sources
The Immunological Functions of Saposins [PDF]
Advances in Immunology, 2010 Saposins or sphingolipid activator proteins (SAPs) are small, nonenzymatic glycoproteins that are ubiquitously present in lysosomes. SAPs comprise the five molecules saposins A-D and the GM2 activator protein. Saposins are essential for sphingolipid degradation and membrane digestion.
Florian Winau
exaly +4 more sources
Saposins (sap) A and C activate the degradation of galactosylceramide in living cells [PDF]
FEBS Letters, 1997 In loading tests using galactosylceramide which had been labelled with tritium in the ceramide moiety, living skin fibroblast lines derived from the original prosaposin-deficient patients had a markedly reduced capacity to degrade galactosylceramide. The
Thierry Levade +2 more
exaly +2 more sources
Saposins A, B, C, and D in Plasma of Patients with Lysosomal Storage Disorders
Clinical Chemistry, 2000 BackgroundEarly diagnosis of lysosomal storage disorders (LSDs), before the onset of irreversible pathology, will be critical for maximum efficacy of many current and proposed therapies. To search for potential markers of LSDs, we measured saposins A, B,
Xiaoyang Qi +2 more
exaly +2 more sources