Results 21 to 30 of about 18,467 (180)

Ewing's Sarcoma [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1976
There are no known external causes of Ewing’ sarcoma, a form of bone cancer, although a small number of cases are linked to genetic abnormalities. This malignancy occurs with remarkable consistency in registry populations across Europe and the United States, including Los Angeles County. Few cases of it occur after age 30.
openaire   +3 more sources

Ewing sarcoma

open access: yesNature Reviews Disease Primers, 2018
Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of 70-80% for patients with standard-risk and localized disease and ~30% for those with metastatic disease.
Grünewald, Thomas G. P.   +8 more
openaire   +6 more sources

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

open access: yesAdvanced Science, 2021
Chromosomal translocation results in development of an Ewing sarcoma breakpoint region 1‐Friend leukemia integration 1 (EWS–FLI1) fusion oncogene in the majority of Ewing sarcoma.
Siyuan Su   +13 more
doaj   +1 more source

Extraskeletal Ewing's sarcoma [PDF]

open access: yesCancer, 1999
Ewing's sarcoma usually is identified as a primary malignancy of bone affecting children and young adults. Extraskeletal Ewing's sarcoma is rare, and very few data are available addressing optimal surgical and oncologic treatment modalities.The authors chose to review retrospectively 24 patients with extraskeletal Ewing's sarcoma treated at the study ...
R, Ahmad   +3 more
openaire   +2 more sources

Gastric Ewing Sarcoma identified on a Meckel's scan

open access: yesRadiology Case Reports, 2020
Ewing Sarcoma is a malignant small round blue cell tumor most commonly found in bones and soft tissues of the axial skeleton and extremities. The Ewing family of tumors, including peripheral neuroectodermal tumor, represent the second most common ...
Lavi Nissim, MD, Gerald Mandell, MD
doaj   +1 more source

Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases

open access: yesCase Reports in Oncology, 2018
Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Montreh Tavakkoli, Lisa Mueller
doaj   +1 more source

Paratesticular Ewing's sarcoma

open access: yesRadiology Case Reports, 2023
This case report follows a 23-year-old man who presented with a painful right scrotal mass which was found to be a paratesticular vascular solid mass on ultrasound, and after uncomplicated orchiectomy, was revealed to be a high-grade extraskeletal Ewing's sarcoma.
Victoria Koshevarova   +5 more
openaire   +3 more sources

Congenital extraskeletal Ewing′s sarcoma of chest wall - A rare case report

open access: yesIndian Journal of Pathology and Microbiology, 2011
Congenital extraskeletal Ewing′s sarcoma or peripheral primitive neuroectodermal tumor is an extremely uncommon and invariably fatal tumor. We report a case of extraskeletal congenital Ewing′s sarcoma in a female fetus delivered at 34 weeks of gestation ...
Bhagyalakshmi Atla   +3 more
doaj   +1 more source

Super‐Enhancer‐Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia Progression

open access: yesAdvanced Science, EarlyView.
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou   +22 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

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