Results 61 to 70 of about 6,019,041 (305)

Characterising the adaptive t-cell immune response against Kaposi’s sarcoma-associated herpesvirus [PDF]

, 2010
Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi’s sarcoma (KS), the most common malignancy in individuals with untreated HIV/AIDS.
Robey, R.C.
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The Scandinavian Sarcoma Group: 30 years' experience

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldThe article offers information on the Scandinavian Sarcoma Group (SSG) whose aim is to uphold and improve the quality of diagnostics, treatment ...
Bauer, Henrik C. F., Bauer, Henrik, Hall, Kirsten Sundby, Lindholm, Paula, Alvegård, Thor, Rydholm, Anders, Sigurdsson, Svante   +6 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Animal Models for Gammaherpesvirus Infections: Recent Development in the Analysis of Virus-Induced Pathogenesis

Pathogens, 2020
Epstein−Barr virus (EBV) is involved in the pathogenesis of various lymphomas and carcinomas, whereas Kaposi’s sarcoma-associated herpesvirus (KSHV) participates in the pathogenesis of endothelial sarcoma and lymphomas.
Shigeyoshi Fujiwara, Hiroyuki Nakamura
doaj   +1 more source

Role of MR-based body composition in children with sarcoma.

, 2023
openBackground. I sarcomi includono un eterogeneo gruppo di tumori dei tessuti molli con una sopravvivenza di circa il 70% a 5 anni. Il trattamento chemioterapico, come già dimostrato in altri gruppi di pazienti adulti e pediatrici, potrebbe causare ...
FAVARO, CRISTIAN
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Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity

Haematologica, 2010
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei, Michael Hummel, Ioannis Anagnostopoulos, Doris Jähne, Renate Arnold, Bernd Dörken, Stephan Mathas, Thomas Benter, Oliver Dudeck, Wolf-Dieter Ludwig, Harald Stein   +10 more
doaj   +1 more source

AIDS and Non AIDS-Related Malignant Lymphoma in Tanzania. [PDF]

, 2006
Malignant lymphoma (ML) in HIV patients, are second in frequency to Kaposi's sarcoma (AKS) as AIDS-defining tumors. In Africa the frequency of AIDS-related lymphoma (ARL) is rare and the findings are controversial.
Ekman, Marianne, Lema, Leonard, Biberfeld, P., Kitinya, J, Carneiro, P, Kitinya, James, Kaaya, EE, Kaaya, Ephata E, Biberfeld, P, Linde, A., Castaños-Velez, E, Lema, L, Carneiro, Primo, Lema, L., Kaaya, E.E., Mwakigonja, A., Biberfeld, Peter, Mwakigonja, A, Carneiro, P., Castaños-Velez, Esmeralda, Mwakigonja, Amos, Ekman, M, Linde, Anika, Castaños-Velez, E., Ekman, M., Linde, A   +25 more
core   +1 more source

New advances in the treatment of Sarcoma

, 2020
The focus of this paper is to cover the evolution in the pharmacologic approach in the treatment of sarcoma. As early as conservative treatment all the way through recent advances and other promising treatments which are under investigation. Nowadays, no
Gal, Ido
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