Results 91 to 100 of about 65,186 (354)
Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis
Advanced Healthcare Materials, EarlyView.Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim +10 more
wiley +1 more source
eLife, 2018 Muscles organise pseudo-crystalline arrays of actin, myosin and titin filaments to build force-producing sarcomeres. To study sarcomerogenesis, we have generated a transcriptomics resource of developing Drosophila flight muscles and identified 40 ...
Maria L. Spletter +10 more
semanticscholar +1 more source
Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue
Advanced Healthcare Materials, EarlyView.Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri +6 more
wiley +1 more source
PLoS Biology, 2018 Sarcomeres are stereotyped force-producing mini-machines of striated muscles. Each sarcomere contains a pseudocrystalline order of bipolar actin and myosin filaments, which are linked by titin filaments.
O. Loison +9 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee +5 more
wiley +1 more source
Approaches to High-Throughput Analysis of Cardiomyocyte Contractility
Frontiers in Physiology, 2020 The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium.
Peter T. Wright +4 more
doaj +1 more source
Meat and Muscle Biology, 2021 Woody breast syndrome is characterized by degenerative changes at the muscle fiber level and accumulation of connective tissue between the fibers.
Crisitina Costandache +2 more
doaj +2 more sources
Journal of applied physiology, 2018 Sarcomere length is a key physiological parameter that affects muscle force output; however, our understanding of the scaling of human muscle from sarcomere to whole muscle is based primarily on cadaveric data.
G. Lichtwark +4 more
semanticscholar +1 more source
The effect of complex training on horizontal power production in rugby union players : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science at Massey University [PDF]
, 2004 The use of strength and power training regimes is common place among elite and recreational athletes. However, the application of such methods as direct determinants of improvement in sporting performance is a controversial and much debated topic because
Graham, David Fraser
core
Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy [PDF]
, 2015 Frameshift mutations in the TTN gene encoding titin are a major cause for inherited forms of dilated cardiomyopathy (DCM), a heart disease characterized by ventricular dilatation, systolic dysfunction, and progressive heart failure. To date, there are no
Alessandra, Moretti +22 more
core +1 more source