Results 81 to 90 of about 51,464 (286)
The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly
eLife, 2016 Actin-based thin filament arrays constitute a fundamental core component of muscle sarcomeres. We have used formation of the Drosophila indirect flight musculature for studying the assembly and maturation of thin-filament arrays in a skeletal muscle ...
Arkadi Shwartz +3 more
doaj +1 more source
Advanced Science, EarlyView.Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans +8 more
wiley +1 more source
Functional and Structural Adaptations of Skeletal Muscle to Microgravity [PDF]
, 2001 Our purpose is to summarize the major effects of space travel on skeletal muscle with particular emphasis on factors that alter function. The primary deleterious changes are muscle atrophy and the associated decline in peak force and power.
Fitts, Robert +2 more
core +1 more source
Deactivation in the rabbit left ventricle induced by constant ejection flow [PDF]
, 1989 A study of pressure generated by the left ventricle after ejection with constant flow for different values of the ejection flow, flow duration, time of flow arrest, and ventricular volume is discussed.
Boom, Herman B.K., Wijkstra, Hessel
core +2 more sources
Advanced Science, EarlyView.A quasi‐periodic Dart‐Kite (QDK) metastructure with a golden‐ratio‐constrained strong–weak bond network simultaneously enhances strength, toughness, and damage tolerance. Its distributed topology enables predictable, tailorable crack paths for precise fracture control and stable mechanics, demonstrating a high‐performance, controllable architecture ...
Tianyu Gao +3 more
wiley +1 more source
Effects of eccentric contraction on force enhancement in rat fast‐twitch muscle
Physiological Reports, 2023 The aim of this study was to elucidate the effects of eccentric contraction (ECC) on force enhancement in rat fast‐twitch skeletal muscle. Gastrocnemius (GAS) muscles were subjected to 200 ECCs in situ by electrical stimulation.
Jiayu Shi, Masanobu Wada
doaj +1 more source
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source
Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy
Frontiers in Physiology, 2018 Mutations in the cardiac actin gene (ACTC1) are associated with the development of hypertrophic cardiomyopathy (HCM). To date, 12 different ACTC1 mutations have been discovered in patients with HCM. Given the high degree of sequence conservation of actin
Evan A. Despond, John F. Dawson
doaj +1 more source
Effect of slaughter age between 5 and 14 months on the quality of sheep meat with specific focus on collagen concentration and solubility : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Animal Science at Massey University, Manawatu, New Zealand [PDF]
, 2017 In New Zealand, pasture-raised lamb is considered the highest quality sheep meat product while hogget is a downgraded product considered to be of poorer quality.
Mashele, Grace Arbogast
core
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.
Thomas D. Gossios +9 more
wiley +1 more source