Results 61 to 70 of about 35,307 (294)
Frontiers in PhysiologyThe transverse–axial tubular system (TATS) is the extension of sarcolemma growing to the cell interior, providing sufficient calcium signaling to induce calcium release from sarcoplasmic reticulum cisternae and stimulate the contraction of neighboring ...
Zuzana Sevcikova Tomaskova +1 more
doaj +1 more source
Approaches to High-Throughput Analysis of Cardiomyocyte Contractility
Frontiers in Physiology, 2020 The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium.
Peter T. Wright +4 more
doaj +1 more source
Breaking sarcomeres by in vitro exercise [PDF]
Scientific Reports, 2016 AbstractEccentric exercise leads to focal disruptions in the myofibrils, referred to as “lesions”. These structures are thought to contribute to the post-exercise muscle weakness and to represent areas of mechanical damage and/or remodelling. Lesions have been investigated in human biopsies and animal samples after exercise. However, this approach does
Zacharias Orfanos +7 more
openaire +2 more sources
Advanced Materials Technologies, EarlyView.We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
Altered Sarcomeric Structure and Function in Woody Breast Myopathy of Avian Pectoralis Major Muscle
Frontiers in Physiology, 2020 The “Woody” or “Wooden” breast disease is a severe myopathy of pectoralis major muscle recently identified within rapidly growing broiler lines all around the world with a prevalence rate around 20%, or even higher.
Jiao Liu +4 more
doaj +1 more source
Schematic representation of the sarcomere cytoskeleton distances.
, 2014 A, an illustration of the sarcomere elementary parts; B, a sarcomere image by electron microscopy; C, a SHGM image of a myofibril; and D, a SHGM intensity profile along the myofibril showing the distances measured to characterize the sarcomere ...
Patricia García-Cañadilla (5661394) +9 more
core +1 more source
Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints
Advanced Robotics Research, EarlyView.This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito +5 more
wiley +1 more source
The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly
eLife, 2016 Actin-based thin filament arrays constitute a fundamental core component of muscle sarcomeres. We have used formation of the Drosophila indirect flight musculature for studying the assembly and maturation of thin-filament arrays in a skeletal muscle ...
Arkadi Shwartz +3 more
doaj +1 more source
Discrete sarcomere length distribution in skeletal muscle
, 1982 We analyzed the microstructure in the first-order laser diffraction line from both resting and tetanically contracting single twitch fibers from frog anterior tibial muscle to see if the distribution of sarcomere lengths is continuous or discrete ...
Ishide, N., Tameyasu, T., Pollack, G.H.
core +1 more source
Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source