Results 111 to 120 of about 35,307 (294)
Alterations in thin filament length during postnatal skeletal muscle development and aging in mice
Frontiers in Physiology, 2014 The lengths of the sarcomeric thin filaments vary in a skeletal muscle-specific manner and help specify the physiological properties of skeletal muscle.
David S Gokhin +4 more
doaj +1 more source
Sarcomere and mitochondria deformation parameters.
, 2013 All data are presented as mean +/− SEM ...
Steven J. Sollott (43475) +5 more
core +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Left ventricular free wall and intraventricular pressure-sarcomere length distributions
, 1980 Sarcomere lengths were measured after pentobarbital anesthesia at five sites through the wall of the formaldehyde solution-fixed cadmium-arrested closed-chest rat left ventricle.
B. R. Grimm, A. F. Grimm, H. L. Lin
core +1 more source
, 2019 Stress vs. sarcomere length experimental data for passive elongation of bundles tested in the present work compared with experimental data on infraspinatus and supraspinatus found by Silldorff et al. [21].
Arturo N. Natali (7821905) +5 more
core +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira +12 more
wiley +1 more source
Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers
Journal of the American Heart Association, EarlyView., 2021 Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes +14 more
wiley +1 more source
Sarcomere length influences proteolysis
, 2007 The overall objective of this research was to determine the role of sarcomere length on postmortem proteolysis as it relates to beef tenderness. The first two studies established that sarcomere length influences postmortem proteolysis of troponin T (TnT)
Weaver, Amanda D
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