Results 131 to 140 of about 51,464 (286)

Effect of soft tissue sample preparation techniques for scanning small‐angle X‐ray scattering experiments

open access: yesJournal of Synchrotron Radiation, EarlyView.
The effect of tissue‐processing techniques, including fixation and embedding, on the structural information obtained from scanning small‐angle X‐ray scattering of muscle and connective tissue has been studied. This provides a framework for sSAXS users working with soft tissues to make an informed choice on the sample preservation method, tailored to ...
Atreyee Acharya   +4 more
wiley   +1 more source

Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans

open access: yesIntegrative Zoology, EarlyView.
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong   +8 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Atrial cardiomyopathy

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala   +1 more
wiley   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Sarcomere Gene Mutation correction [PDF]

open access: yesEuropean Heart Journal, 2018
Sanjiv, Kaul   +2 more
openaire   +2 more sources

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

open access: yesThe FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar   +3 more
wiley   +1 more source

Sustained Idiopathic Outflow Tract Ventricular Tachycardia: Clinical Evidence for RVOT Predominance

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Idiopathic outflow tract premature ventricular contractions (PVCs) are most commonly localized in the right ventricular outflow tract (RVOT). The clinical significance of sustained outflow tract ventricular tachycardia (OT‐VT) regarding any predominance to one specific anatomic area remains uncertain.
Moneeb Khalaph   +16 more
wiley   +1 more source

Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies

open access: yeseLife
The giant striated muscle protein titin integrates into the developing sarcomere to form a stable myofilament system that is extended as myocytes fuse.
Judith Hüttemeister   +9 more
doaj   +1 more source

Axial muscle‐fibre orientations in larval zebrafish

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 517-533, April 2025.
In 4 days post‐fertilization zebrafish larvae, the fast axial muscle fibres follow helical trajectories that taper towards the tail. Adjacent muscle fibres form substantial angles relative to each other to accommodate this pattern. Using a novel semi‐automatic method, we quantified 3D fibre angles over the whole muscle volume.
Noraly M. M. E. van Meer   +3 more
wiley   +1 more source

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