Results 141 to 150 of about 51,464 (286)
Architecture of lower leg muscles in children: Reference curves and potential mechanisms of growth
Journal of Anatomy, EarlyView.Muscle architecture (physiological cross‐sectional area, fascicle lengths and pennation angle) was measured from multimodal MRI scans of the lower legs of 197 children aged ≤15 years. We showed that lower leg muscle volumes (product of PCSA and fascicle length) increase primarily through increases in PCSA (transverse growth) rather than increases in ...
Brian V. Y. Chow +12 more
wiley +1 more source
Hitting the Detection Limit in cAMP Signaling
Function, 2022 Florencia Klein +2 more
doaj +1 more source
Oral Diseases, EarlyView.ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira +7 more
wiley +1 more source
Exercise‐induced dynamic hyperinflation in chronic obstructive pulmonary disease
Experimental Physiology, EarlyView.Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pulmonary vasculature lead to increased resistive, elastic and threshold loads and impaired capacity of the respiratory muscle pump. COPD
Rebecca F. D'Cruz +2 more
wiley +1 more source
Biological properties of α-actinin-2 and its role and mechanisms in disease development
Frontiers in Physiologyα-Actinin-2 (encoded by the ACTN2 gene) is a critical cytoskeletal protein predominantly expressed in skeletal and cardiac muscle, where it anchors actin filaments to the sarcomeric Z-disk. While its structural role is well-established, emerging evidence
Juan Meng +7 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon +2 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract This systematic review summarizes the available evidence on respiratory muscle endurance training involving voluntary isocapnic hyperpnoea among patients with chronic diseases. It includes both randomized and non‐randomized controlled trials implementing this exercise training modality performed either alone or in combination with other ...
Hélène Laurent +3 more
wiley +1 more source
In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells
Experimental Physiology, EarlyView.Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene +4 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
P. H. C. Mesquita +3 more
wiley +1 more source