Results 161 to 170 of about 51,464 (286)

The roles of the microtubule cytoskeletal network in cardiac mechanobiology. [PDF]

J Cell Sci
Murphy JF, Li X.
europepmc   +1 more source

Computational model of haemodynamics during atrial fibrillation

The Journal of Physiology, EarlyView.
Abstract figure legend We developed a simplified computational model that replicates patient‐specific haemodynamics during both normal sinus rhythm and atrial fibrillation (AF). Our computational model comprises: (1) an electrical subsystem that generates unco‐ordinated atrial and irregular ventricular activation times characteristic of AF and (2) a ...
Felix Plappert, Pim J.A. Oomen, Clara E. Jones, Emmanouil Charitakis, Lars O. Karlsson, Pyotr G. Platonov, Mikael Wallman, Frida Sandberg   +7 more
wiley   +1 more source

Editorial: Recent Advances on Myocardium Physiology, Volume II

Frontiers in Physiology, 2023
Norio Fukuda, Henk Granzier, Shin’ichi Ishiwata, Sachio Morimoto   +3 more
doaj   +1 more source

Activity-dependent remodeling of muscle architecture during distinct locomotor behaviors in Caenorhabditis elegans. [PDF]

Biol Open
Fazyl A, Anbu A, Kollbaum S, Vidal-Gadea AG.   +3 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Commentary: Nanoscopy reveals the layered organization of the sarcomeric H-zone and I-band complexes

Frontiers in Cell and Developmental Biology, 2020
Nicanor González-Morales, Frieder Schöck   +1 more
doaj   +1 more source

Cell shape and maturation impacts α-actinin-2 tension in iPSC-derived cardiomyocytes. [PDF]

APL Bioeng
Dutta PK, Toth JM, Sundaram S, Chen X, Chopra A, Ewoldt JK, Cloonan P, Gao X, LaCroix AS, Hoffman BD, Shenoy VB, Seidman CE, Seidman JG, Chen CS, Eyckmans J.   +14 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Osimertinib induces reversible cardiac dysfunction through the GATA4-MYLK3-MYL2 axis. [PDF]

Eur Heart J
Zhang K, Ayala A, Norambuena-Soto I, Agnihotri V, Shu T, Nenninger C, Wang Y, Echevarria B, Aboagye J, Huang K, Espitia-Corredor J, Wu X, Chen ZB, Deng Y, Perry JJP, Raz DJ, Yang H, Cheng P, Fu G, Wang ZV, Rhee JW.   +20 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source