Results 171 to 180 of about 29,455 (242)

Phosphate and acidosis cause fibre type‐specific changes to cellular and molecular contractile mechanics at 37°C in skeletal muscle from older adults

Experimental Physiology, Volume 111, Issue 8, Page 3753-3771, 1 August 2026.
Abstract Intracellular accumulation of hydrogen ions (H+) and inorganic phosphate (Pi) has temperature‐dependent effects on single‐fibre contractile function between 10°C and 30°C. In vivo, human skeletal muscle temperatures range between 35‐39°C, and although contractile function is highly dependent on temperature, the effects of fatigue‐inducing [H+]
Brent A. Momb, Jane A. Kent, Stuart R. Chipkin, Mark S. Miller   +3 more
wiley   +1 more source

Western Diet-Induced Impairment of Left Atrium Cardiomyocyte Contractility in Female Wistar Rats Is Associated with Slowdown in the Cross-Bridge Cycle and Dephosphorylation of cMyBP-C. [PDF]

Int J Mol Sci
Mukhlynina E, Butova X, Myachina T, Simonova R, Antonets Y, Leiberova A, Kochurova A, Gusarova E, Chumarnaya T, Kopylova G, Shchepkin D.   +10 more
europepmc   +1 more source

Strategies for the Selection and Application of Biological Scaffolds in Organ‐on‐a‐Chip Systems

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Organ‐on‐a‐chip (OoC) serves as a promising microphysiological platform for drug screening, disease modeling, and toxicity assessment. Biomimetic scaffolds are core components that determine the performance of OoC systems by mimicking the in vivo extracellular microenvironment.
Yichi Zhang, Ning Zhang, Linkai Jiang, Zhilong Zhou, Yuwei Zhang, Yuwen Wang, Yiting Lei, Ning Hu, Zhong Alan Li   +8 more
wiley   +1 more source

Development of a vascularized multi-organoid-on-a-chip to model the heart-islet axis in diabetic cardiomyopathy. [PDF]

Bioact Mater
Yang Z, Lin L, Jiang J, Wang Y, Li F, Li X, Fang J, Xu L, Li H, Du L, Liu Z, Liang R, Wang S, Dong X, Hu S, Duan Y, Qin H, Kong D.   +17 more
europepmc   +1 more source

Advanced in vitro cardiac models for drug evaluation: integration of organoids, engineered tissues, and microphysiological systems. [PDF]

Microsyst Nanoeng
Kim YH, Son YH, Choi Y, Kim MS, Park SJ, Lee KY.   +5 more
europepmc   +1 more source

Mechanistic insights into the divergent tenderness evolution of Wenchang and Huangma chickens during coconut water stewing. [PDF]

Food Chem X
Liu L, Wu Y, Han D, Zhang C, Huang F.
europepmc   +1 more source

Gene Testing Across Phenotypes of Hypertrophic Cardiomyopathy. [PDF]

JACC Case Rep
Bavishi A, Nazif K, Martinez MW.
europepmc   +1 more source

Generation of a functional fluorescently-tagged PFN-3 profilin transgene in <i>Caenorhabditis elegans</i>. [PDF]

MicroPubl Biol
Kimmich M, Pruyne D.
europepmc   +1 more source

Top-Down Proteomics of Skinned Human Muscle Fibers Reveals Proteoform-Resolved Fiber-to-Fiber Variability. [PDF]

J Mass Spectrom
Wilson MC, Gao Z, Lopez JR, Zhu Y, Olszewski SS, Konopka AR, Diffee GM, Ge Y.   +7 more
europepmc   +1 more source

FHOD3 deficiency disrupts sarcomere organization and activates caMKII signaling in human stem cell-derived cardiomyocytes. [PDF]

Stem Cell Res Ther
Wei M, Hou X, Zhang S, Hu X, Chen X, Gao Z, Xu S, Shi Z, Zhu M, Lan F, Cui M.   +10 more
europepmc   +1 more source