Results 121 to 130 of about 42,993 (322)

Finally, We Can Relax: A New Generation of Muscle Models that Incorporate Sarcomere Compliance [PDF]

, 2016
Michael Regnier, Yuanhua Cheng
openalex   +1 more source

From sarcomeres to whole muscles [PDF]

Journal of Experimental Biology, 1985
ABSTRACT The series connection of sarcomeres in a muscle raises the possibility of instabilities due to some sarcomeres being capable of greater isometric tension than others, due to non-uniform activation, cross-sectional area or sarcomere length.
openaire   +2 more sources

Nanoparticle‐integrated electrostimulation‐responsive biomaterials: Innovations in drug delivery and tissue repair in clinical regenerative medicine

Interdisciplinary Medicine, EarlyView.
Schematic representation of nanoparticle‐integrated electrostimulation‐responsive biomaterials for controlled drug delivery and tissue regeneration. Electroactive scaffolds including conductive polymers, electroresponsive hydrogels, and piezoelectric matrices are shown incorporating therapeutic nanoparticles (such as iron oxide, silver, and carbon ...
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Relationship of muscle morphology to hip displacement in cerebral palsy: a pilot study investigating changes intrinsic to the sarcomere

Journal of Orthopaedic Surgery and Research, 2019
Background Cerebral palsy (CP) is the most common cause of childhood disability, typified by a static encephalopathy with peripheral musculoskeletal manifestations—most commonly related to spasticity—that are progressive with age. Hip displacement is one
Kelly A. Larkin-Kaiser, Jason J. Howard, Timothy Leonard, Venus Joumaa, Luke Gauthier, Karl Logan, Benjamin Orlik, Ron El-Hawary, Walter Herzog   +8 more
doaj   +1 more source

Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte

, 2023
Jia Li, Joakim Sundnes, Yufeng Hou, Martin Laasmaa, Marianne Ruud, Andreas Unger, Terje R. Kolstad, Michael Frisk, Per Andreas Norseng, Limin Yang, Ingunn E. Setterberg, Estela Santos‐Alves, Michaeljohn Kalakoutis, Ole M. Sejersted, Johanna T. Lanner, Wolfgang A. Linke, Ida G. Lunde, Pieter P. de Tombe, William E. Louch   +18 more
openalex   +1 more source

The role of sarcomere length non-uniformities in residual force enhancement of skeletal muscle myofibrils

Royal Society Open Science, 2016
The sarcomere length non-uniformity theory (SLNT) is a widely accepted explanation for residual force enhancement (RFE). RFE is the increase in steady-state isometric force following active muscle stretching. The SLNT predicts that active stretching of a
K. Johnston, A. Jinha, W. Herzog
semanticscholar   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

Nucleus-dependent sarcomere assembly is mediated by the LINC complex

Molecular Biology of the Cell, 2016
Although significant progress has been made in understanding the mechanisms of nuclear movement, the functions of nuclear movement have proven more elusive.
Alexander L. Auld, Eric S. Folker
semanticscholar   +1 more source

Oxidative Stress and Sarcomeric Proteins [PDF]

Circulation Research, 2013
Oxidative stress accompanies a wide spectrum of clinically important cardiac disorders, including ischemia/reperfusion, diabetes mellitus, and hypertensive heart disease. Although reactive oxygen species (ROS) can activate signaling pathways that contribute to ischemic preconditioning and cardioprotection, high levels of ROS induce structural ...
openaire   +2 more sources

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source