Results 141 to 150 of about 42,993 (322)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Axial muscle‐fibre orientations in larval zebrafish

Journal of Anatomy, Volume 246, Issue 4, Page 517-533, April 2025.
In 4 days post‐fertilization zebrafish larvae, the fast axial muscle fibres follow helical trajectories that taper towards the tail. Adjacent muscle fibres form substantial angles relative to each other to accommodate this pattern. Using a novel semi‐automatic method, we quantified 3D fibre angles over the whole muscle volume.
Noraly M. M. E. van Meer, Johan L. van Leeuwen, Henk Schipper, Martin J. Lankheet   +3 more
wiley   +1 more source

Cardiac troponin T is essential in sarcomere assembly and cardiac contractility [PDF]

, 2002
Amy J. Sehnert, Anja Huq, Brant M. Weinstein, Charline Walker, Mark C. Fishman, Didier Y. R. Stainier   +5 more
openalex   +1 more source

Compound Mutation in Cardiac Sarcomere Proteins Is Associated with Increased Risk for Major Arrhythmic Events in Pediatric Onset Hypertrophic Cardiomyopathy [PDF]

, 2021
Kathrin Pollmann, Emanuel Kaltenecker, Julia Schleihauf, Peter Ewert, Agnes Görlach, Cordula M. Wolf   +5 more
openalex   +1 more source

Sarcomere Gene Mutation correction [PDF]

European Heart Journal, 2018
Sanjiv, Kaul, Stephen B, Heitner, Shoukhrat, Mitalipov   +2 more
openaire   +2 more sources

Architecture of lower leg muscles in children: Reference curves and potential mechanisms of growth

Journal of Anatomy, EarlyView.
Muscle architecture (physiological cross‐sectional area, fascicle lengths and pennation angle) was measured from multimodal MRI scans of the lower legs of 197 children aged ≤15 years. We showed that lower leg muscle volumes (product of PCSA and fascicle length) increase primarily through increases in PCSA (transverse growth) rather than increases in ...
Brian V. Y. Chow, Suzanne Davies, Catherine Morgan, Caroline D. Rae, David I. Warton, Iona Novak, Ann Lancaster, Gordana C. Popovic, Rodrigo R. N. Rizzo, Claudia Y. Rizzo, Iain K. Ball, Robert D. Herbert, Bart Bolsterlee   +12 more
wiley   +1 more source

Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies

eLife
The giant striated muscle protein titin integrates into the developing sarcomere to form a stable myofilament system that is extended as myocytes fuse.
Judith Hüttemeister, Franziska Rudolph, Michael H Radke, Claudia Fink, Dhana Friedrich, Stephan Preibisch, Martin Falcke, Eva Wagner, Stephan E Lehnart, Michael Gotthardt   +9 more
doaj   +1 more source

Isometric training at longer muscle–tendon complex lengths: A potential countermeasure to impaired neuro‐muscle–tendon function during space travel

Experimental Physiology, EarlyView.
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon, Andy Sanderson, Hans Degens   +2 more
wiley   +1 more source

The myotonic dystrophy type 2 (DM2) gene product zinc finger protein 9 (ZNF9) is associated with sarcomeres and normally localized in DM2 patients' muscles [PDF]

, 2010
Roberto Massa, Maria Beatrice Panico, Sara Caldarola, Francesca R. Fusco, Patrizia Sabatelli, Chiara Terracciano, Annalisa Botta, Giuseppe Novelli, Giorgio Bernardi, Fabrizio Loreni   +9 more
openalex   +1 more source