Results 191 to 200 of about 65,186 (354)
Aging Cell, EarlyView.Inhibition of MMP9/13 restores both muSC behaviour and regeneration, while macrophage ablation enhances muSC recruitment to the injury, but fails to improve muscle repair in telomerase‐deficient zebrafish larvae. ABSTRACT Ageing progressively impairs skeletal muscle regeneration, contributing to reduced mobility and quality of life. While the molecular
Yue Yuan, Carlene Dyer, Robert D. Knight
wiley +1 more source
Organ‐Specific Dedifferentiation and Epigenetic Remodeling in In Vivo Reprogramming
Aging Cell, EarlyView.Transient in vivo expression of Yamanaka factors (OSKM) enhances regenerative competence and rejuvenation across multiple tissues. We highlight mechanistic links between injury‐induced dedifferentiation and OSKM reprogramming, while emphasizing safety challenges and the need for precise spatiotemporal control to enable clinical translation.
Beom‐Ki Jo +4 more
wiley +1 more source
Artificial Organs, EarlyView.Transverse placement of electrical muscle stimulation (EMS) electrodes across muscle fibers elicits localized contractions, facilitating greater active stretching (AS) of regions containing myofascial trigger points. This EMS + AS approach mimics passive stretching, with EMS providing resistance force similar to that typically applied by a therapist's ...
Seekaow Churproong +3 more
wiley +1 more source
Lack of effect of isoproterenol on unloaded velocity of sarcomere shortening in rat cardiac trabeculae. [PDF]
, 1991 Pieter P. de Tombe, H E ter Keurs
openalex +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
Cell Proliferation, EarlyView.HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang +4 more
wiley +1 more source
THE VARIATION IN THERMOELASTICITY WITH SARCOMERE LENGTH IN FROG'S STRIATED MUSCLE
, 1975 Saburo Matsubara
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The FEBS Journal, EarlyView.The damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel) compared with the wild‐type littermates. These changes are accompanied by a wide‐ranging impact, including phenotypical (middle panel) and molecular (right panel) changes ...
Sanna‐Maria Karppinen +15 more
wiley +1 more source