Results 201 to 210 of about 51,464 (286)

A homozygous variant in cardiac troponin I3, TNNI3, causes severe pediatric restrictive cardiomyopathy. [PDF]

HGG Adv
Kühnisch J, Barnett CL, Brendel J, Berklite L, Villa C, Seifert W, Klaassen S, Klingel K, Weaver KN.   +8 more
europepmc   +1 more source

Cultivated Meat and the Future of Food Systems: Promise, Progress, and Challenges

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
An overview of cultivated meat as an emerging food‐production platform, contrasting the environmental burdens of conventional livestock with key biomanufacturing steps—from cell biopsy and proliferation to differentiation, scaffolding, and final product formation.
Sungmin Kim, Keon‐Ha Park, Seong‐Jae Park, Yun‐Gwi Park, Sung‐Hwan Moon   +4 more
wiley   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

Journal of Applied Toxicology, Volume 46, Issue 4, Page 1076-1082, April 2026.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

The varied functions of the giant muscle scaffold protein obscurin. [PDF]

Front Cell Dev Biol
Di Paola JN, Schöck F.
europepmc   +1 more source

Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 8, April 2026.
Through single‐cell RNA‐sequencing and high‐dimensional weighted gene co‐expression network analysis, two monocyte‐related biomarkers (CSF3R, IFITM3) were identified in the peripheral blood of Parkinson's disease. Molecular docking revealed two targeted drugs (Indirubin and Retinoic acid).
Zhiwei Bao, Shao Zhi, Mao Jie
wiley   +1 more source

Dystrophin Loss in Engineered Heart Tissues Recapitulates Clinically Relevant Aspects of Dystrophic Cardiomyopathy. [PDF]

J Biomech Eng
Goldstein AJ, Leahy TP, Mack DL, Sniadecki NJ.   +3 more
europepmc   +1 more source

Single‐Nucleus RNA Sequencing Reveals Muscle Fiber Cell Heterogeneity During Human Skeletal Muscle Aging

Aging Cell, Volume 25, Issue 4, April 2026.
Aging was characterized by a state transition, accompanied by denervation and fatty infiltration. The aged microenvironment was globally altered. BMP and Laminin signaling were involved in enhanced FAPs communicating to myofibers. ABSTRACT Aging impairs skeletal muscle mass and function, but the cell‐type–resolved transcriptional states and ...
Caixia Gong, Li Wu, Ange Wang, Nan Hua, Chengfan Qin, Shunmei Huang, Xia Zhang, Yunmei Yang, Jing Chen, Qin Zhang   +9 more
wiley   +1 more source

Embedding muscle fibers in hydrogel improves viability and preserves contractile function during prolonged ex vivo culture. [PDF]

J Gen Physiol
Vonk LA, Esen O, Hoomoedt D, Balesar RMN, Ottenheijm CAC, Kirby TJ.   +5 more
europepmc   +1 more source

Dysregulated Sheddase Signalling as a Molecular Driver of Plaque Instability Revealed by Integrative Transcriptomics

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Atherosclerosis is a major cause of mortality due to chronic and progressive low‐grade inflammation and fibroproliferative remodelling of the intima of arteries. Comprehensive understanding of the interplay between plaque biology and the mechanisms underlying plaque vulnerability and rupture is essential.
Alaa G. Alahmadi, Hind A. Alkhatabi, Reem M. Alotibi, Wedad M. Albeshri, Mohammed El‐Mezgueldi, Ammar AL‐Farga, Peter Natesan Pushparaj   +6 more
wiley   +1 more source

Titin Cardiomyopathy, Emerging Evidence: More Than A Big Heart. [PDF]

Curr Cardiol Rep
Angriman F, Bortolotti F, Perotto M, Artioli R, Radesich C, Paldino A, Collesi C, Zacchigna S, Sinagra G, Dal Ferro M.   +9 more
europepmc   +1 more source