International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 6, June 2026.Partial continuous‐flow left ventricular assist device (LVAD) treatment of peripartum cardiomyopathy provides greater functional improvement for higher than lower disease severity. The left ventricle and LVAD jointly generate ventricular output for mild functional impairment, where the left ventricular contribution decreases with increasing LVAD ...
Juliet Nagawa +8 more
wiley +1 more source
Western Diet-Induced Impairment of Left Atrium Cardiomyocyte Contractility in Female Wistar Rats Is Associated with Slowdown in the Cross-Bridge Cycle and Dephosphorylation of cMyBP-C. [PDF]
Int J Mol SciMukhlynina E +10 more
europepmc +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
Advanced Genetics, Volume 7, Issue 2, June 2026.This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Advanced in vitro cardiac models for drug evaluation: integration of organoids, engineered tissues, and microphysiological systems. [PDF]
Microsyst NanoengKim YH +5 more
europepmc +1 more source
Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries +2 more
wiley +1 more source
Mechanistic insights into the divergent tenderness evolution of Wenchang and Huangma chickens during coconut water stewing. [PDF]
Food Chem XLiu L, Wu Y, Han D, Zhang C, Huang F.
europepmc +1 more source
A Novel Surgical Approach to Induce an Ankle Joint Contracture in Rats
Journal of Orthopaedic Research, Volume 44, Issue 6, June 2026.ABSTRACT Our primary aim was to establish a novel surgical immobilization approach to induce a persistent ankle plantar‐flexion contracture in the Wistar rat. A stainless steel suture was placed in experimental animals (n = 14) and pulled taut between the calcaneal bone and the knee joint, restricting dorsal‐flexion while still allowing for limited ...
Guido Geusebroek +5 more
wiley +1 more source
Gene Testing Across Phenotypes of Hypertrophic Cardiomyopathy. [PDF]
JACC Case RepBavishi A, Nazif K, Martinez MW.
europepmc +1 more source
Aging Impairs Macrophage Phagocytosis Through Mitochondrial ROS‐Induced Collagen Production
Aging Cell, Volume 25, Issue 6, June 2026.Aging compromises macrophage phagocytosis via the mitochondrial ROS‐driven overproduction of intracellular collagen. This excess collagen physically binds F‐actin, paralyzing cytoskeletal turnover; however, mtROS scavenging successfully rescues actin dynamics and restores phagocytic capacity.
Yuming Wang +14 more
wiley +1 more source
Generation of a functional fluorescently-tagged PFN-3 profilin transgene in <i>Caenorhabditis elegans</i>. [PDF]
MicroPubl BiolKimmich M, Pruyne D.
europepmc +1 more source