Results 131 to 140 of about 16,570 (272)

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner, Fabio Frangiamore, Frédéric Sonak, Josef Madl, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +6 more
wiley   +1 more source

Computational model of haemodynamics during atrial fibrillation

The Journal of Physiology, EarlyView.
Abstract figure legend We developed a simplified computational model that replicates patient‐specific haemodynamics during both normal sinus rhythm and atrial fibrillation (AF). Our computational model comprises: (1) an electrical subsystem that generates unco‐ordinated atrial and irregular ventricular activation times characteristic of AF and (2) a ...
Felix Plappert, Pim J.A. Oomen, Clara E. Jones, Emmanouil Charitakis, Lars O. Karlsson, Pyotr G. Platonov, Mikael Wallman, Frida Sandberg   +7 more
wiley   +1 more source

PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more

Biology Open
Mélina Baheux Blin, Vincent Loreau, Frank Schnorrer, Pierre Mangeol   +3 more
doaj   +1 more source

Sarcomere length distribution quantification in whole muscle frozen sections

, 2016
Shawn M. O’Connor, Elton J. Cheng, Kevin W. Young, Samuel R. Ward, Richard L. Lieber   +4 more
openalex   +2 more sources

Correction to: Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function [PDF]

, 2020

openalex   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała, Marta Białobrzeska, Józef Dulak, Urszula Florczyk‐Soluch   +3 more
wiley   +1 more source

Human Variant in the Cardiac Troponin I Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Elizabeth Silver, Jason M. Duran, Betul Beyza Gunes, Axel J. Fenwick, Sofie Maisel, Tsui‐Min Wang, Ana Maria Manso, Marina Sampaio Cruz, Yusu Gu, Joshua Fong, Aysen Shathaya, Chao Chen, Angel Soto‐Hermida, Wei Feng, Yoshitake Cho, Julius Bogomolovas, Jill M. Gelow, Ahmad Masri, Kelly A. Frazer, Robert S. Ross, Ju Chen, Catherine A. Makarewich, Anthony Cammarato, Andrew D. McCulloch, Paul Bushway, Eric D. Adler   +25 more
doaj   +1 more source

A mechanism for sarcomere breathing: volume change and advective flow\n within the myofilament lattice [PDF]

, 2019
Julie A. Cass, Chelsea Williams, Tom Irving, Eric Lauga, Sage Malingen, T. L. Daniel, Simon Sponberg   +6 more
openalex   +1 more source

Reference Methods for Measuring Skeletal Muscle Mass: A Critical Perspective

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Skeletal muscle (SM) is an integral organ component in the pathophysiology of many acute and chronic diseases. But is there a ‘gold’ standard or accepted reference method for quantifying the amount and composition of human SM mass? Exploring that question led us to recognize the existence of a SM measurement paradigm that divides methods into ...
Steven B. Heymsfield, Houchun H. Hu, Edvin Johanssen, Sophia Ramirez, Gabriela de Oliveira Lemos, Maria Cristina Gonzalez, Carla M. Prado, Jonathan P. Bennett   +7 more
wiley   +1 more source

Repercussions on sarcomeres of the myotendinous junction and the myofibrillar type adaptations in response to different trainings on vertical ladder

, 2020
Lara Caetano Rocha, Jurandyr Pimentel Neto, Jossei Soares de Sant'Ana, Carolina dos Santos Jacob, Gabriela Klein Barbosa, Walter Krause Neto, Ii‐Sei Watanabe, Adriano Polican Ciena   +7 more
openalex   +2 more sources