Results 71 to 80 of about 11,481 (144)

Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy [PDF]

, 2001
Cypher is a member of a recently emerging family of proteins containing a PDZ domain at their NH(2) terminus and one or three LIM domains at their COOH terminus.
Po-Hsien Chu, Knoll, Gudrun, Qiang Zhou, Chu, Po-Hsien, Cheng, Ching-Feng, G. Diane Shelton, Evans, Sylvia, Sylvia Evans, Huang, Chenqun, Ching-Feng Cheng, Ju Chen, Shelton, G Diane, Chenqun Huang, Maryann E. Martone, Gudrun Knoll, Martone, Maryann E, Zhou, Qiang, Chen, Ju   +17 more
core   +1 more source

Tuning of mitochondrial pathways by muscle work: from triggers to sensors and expression signatures

, 2009
Performance of striated muscle relies on the nerve-driven activation of the sarcomeric motor and coupled energy supply lines. This biological engine is unique; its mechanical and metabolic characteristics are not fixed, but are tailored by functional ...
Flueck, Martin
core   +1 more source

RBM24 Is a Major Regulator of Muscle-Specific Alternative Splicing [PDF]

, 2014
SummaryCell-type-specific splicing generates numerous alternatively spliced transcripts playing important roles for organ development and homeostasis, but only a few tissue-specific splicing factors have been identified.
Khrameeva, Ekaterina, Licht, Thomas, Braun, Thomas, Yang, Jiwen, Schneider, Andre, Bindereif, Albrecht, Hung, Lee-Hsueh, Kostin, Sawa, Looso, Mario   +8 more
core   +1 more source

The Effects of Swiprosin-1 on the Formation of Pseudopodia-Like Structures and β-Adrenoceptor Coupling in Cultured Adult Rat Ventricular Cardiomyocytes - Fig 1

, 2016
De- and redifferentiation of ARVC in culture with 20% FCS (A) Freshly isolated ARVC with their typical rod shape form (Day 0) completely rounded down by degrading sarcomeres starting in the periphery (Day 1) in the first days of culture.
Martin Weber (1941247), Franziska Nippert (3589883), Klaus-Dieter Schlüter (339076), Rolf Schreckenberg (339079), Antonia Hess (3589880)   +4 more
core   +1 more source

ULTRASTRUCTURAL FEATURES OF CARDIOMYOCYTE CONTRACTILE APPARATUS IN RAT OFFSPRING HEARTS FOLLOWING MATERNAL CHRONIC ALCOHOL INTOXICATION

Проблеми екології та медицини
Background. The mechanisms underlying the development of the heart contractile apparatus and the distribution of myofibrils in cardiomyocytes following intrauterine ethanol intoxication continue to be a topic of significant debate.
I.V. Tverdokhlib, D.G. Marchenko
doaj   +1 more source

A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo

, 2009
Although it is well known that mutations in the cardiac essential myosin light chain-1 (cmlc-1) gene can cause hypertrophic cardiomyopathy, the precise in vivo structural and functional roles of cMLC-1 in the heart are only poorly understood.
Fishman, Mark, Rottbauer, Wolfgang, Hess, Alexander, Meder, Benjamin, Hassel, David, Vogel, Britta, Laufer, Christina, Katus, Hugo A, Just, Steffen, Marquart, Sabine   +9 more
core   +1 more source

Morphologic study of different treatments for gastrocnemius muscle contusion in rats

Revista Brasileira de Ortopedia
OBJECTIVE: Evaluate the effects of ultrasound and stretching in morphology after rat muscle contusion. METHODS: Male Wistar rats (n = 35, 8-9 weeks, 271 ± 14 g) were divided into five groups: control group (CG = 3); lesion group (LG = 8); lesion ...
Ana Carolina Brandt de Macedo, Julye Leiko Ywazaki, Rafael Michel de Macedo, Lucia Noronha, Anna Raquel Silveira Gomes   +4 more
doaj   +1 more source

POSTNATAL REMODELING OF THE MYOFIBRILLAR APPARATUS IN TYPICAL RAT CARDIOMYOCYTES AFTER EXPOSURE TO CHRONIC PRENATAL HYPOXIA

Проблеми екології та медицини
Introduction. Chronic prenatal hypoxia is a significant factor affecting the development of the fetal myocardium, particularly the formation and remodeling of the myofibrillar apparatus in cardiomyocytes.
I.V. Tverdokhlib, P.A. Kobeza
doaj   +1 more source

Does longer-muscle length resistance training cause greater longitudinal growth? A systematic review.

We will aim to review the existing data on sarcomerogenesis or proxy measurements such as fascicle length and RT at different muscle lengths alongside muscle hypertrophy ...
Menno Henselmans, Daniel Plotkin, Bret Contreras, Patroklos Androulakis-Korakakis, Milo Wolf, Brad Jon Schoenfeld, Michael D. Roberts, Martino Franchi   +7 more
core   +1 more source

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer

The Journal of Clinical Investigation
Heterozygous truncating variants in the sarcomere protein titin (TTN) are the most common genetic cause of heart failure. To understand mechanisms that regulate abundant cardiomyocyte (CM) TTN expression, we characterized highly conserved intron 1 ...
Yuri Kim, Seong Won Kim, David Saul, Meraj Neyazi, Manuel Schmid, Hiroko Wakimoto, Neil Slaven, Joshua H. Lee, Olivia Layton, Lauren K. Wasson, Justin H. Letendre, Feng Xiao, Jourdan K. Ewoldt, Konstantinos Gkatzis, Peter Sommer, Bénédicte Gobert, Nicolas Wiest-Daesslé, Quentin McAfee, Nandita Singhal, Mingyue Lun, Joshua M. Gorham, Zolt Arany, Arun Sharma, Christopher N. Toepfer, Gavin Y. Oudit, William T. Pu, Diane E. Dickel, Len A. Pennacchio, Axel Visel, Christopher S. Chen, J.G. Seidman, Christine E. Seidman   +31 more
doaj   +1 more source