Results 61 to 70 of about 11,481 (144)

Single-step stretching vs multi-step stretching of skeletal muscle.

, 2013
A total stretch of is applied ad hoc (left) and gradually (right). Sarcomerogenesis is simulated for over period of eight weeks.
Oscar J. Abilez (304734), Alexander M. Zöllner (304732), Ellen Kuhl (304737), Markus Böl (304735)   +3 more
core   +1 more source

Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin‐deficient muscle

The Journal of Physiology, Volume 602, Issue 20, Page 5229-5245, 15 October 2024.
Abstract figure legend Mavacamten, a myosin‐centred small molecule, directly enhances myosin ATP‐conserving biochemical state in muscle fibres from patients with nemaline myopathy (or mice lacking nebulin). However, in vivo treatment with Mavacamten for 4 weeks (in mice lacking nebulin) does not have significant effects on the muscle fibre energetic ...
Jenni Laitila, Robert A. E. Seaborne, Natasha Ranu, Justin S. Kolb, Carina Wallgren‐Pettersson, Nanna Witting, John Vissing, Juan Jesus Vilchez, Edmar Zanoteli, Johanna Palmio, Sanna Huovinen, Henk Granzier, Julien Ochala   +12 more
wiley   +1 more source

Skeletal muscle mechanics, energetics and plasticity

Journal of NeuroEngineering and Rehabilitation, 2017
The following papers by Richard Lieber (Skeletal Muscle as an Actuator), Thomas Roberts (Elastic Mechanisms and Muscle Function), Silvia Blemker (Skeletal Muscle has a Mind of its Own: a Computational Framework to Model the Complex Process of Muscle ...
Richard L. Lieber, Thomas J. Roberts, Silvia S. Blemker, Sabrina S. M. Lee, Walter Herzog   +4 more
doaj   +1 more source

The effect of neuromuscular electrical stimulation applied at different muscle lengths on muscle architecture and sarcomere morphology in rats

The Anatomical Record, Volume 307, Issue 2, Page 356-371, February 2024.
Abstract Neuromuscular electrical stimulation (NMES) is often used to increase muscle strength and functionality. Muscle architecture is important for the skeletal muscle functionality. The aim of this study was to investigate the effects of NMES applied at different muscle lengths on skeletal muscle architecture.
Nehir Uçar, Hakan Öner, Murat Abdulgani Kuş, Harun Karaca, Tüzün Fırat   +4 more
wiley   +1 more source

Serial Sarcomere Number and Functional Adaptations in Aging Muscle [PDF]

Muscle fascicle length (FL) decreases with age due to the loss of serial sarcomere number (SSN), contributing to declines in muscle mechanical performance.
Hinks, Avery
core   +1 more source

Stretching skeletal muscle.

, 2013
In a controlled limb lengthening model in rabbits, the radius and the ulna of the left forearm are lengthened by 4% inducing a stretch of 1.14 in the extensor digitorum lateralis muscle.
Oscar J. Abilez (304734), Alexander M. Zöllner (304732), Ellen Kuhl (304737), Markus Böl (304735)   +3 more
core   +1 more source

The relationship between sarcomerogenesis and the development of tissue organization of the myocardium in embryonic chicken cardiogenesis

Morphologia
Актуальність. Загальною основою для розуміння того, яким чином обмежений діапазон скорочення саркомерів забезпечує серцевий викид під час систоли, є аналіз онтогенетичного утворення та локальних особливостей розвитку міофібрилярної структури кардіоміоцитів за рахунок зіставлення фазових станів міокарда.
H.S. Maslak, R.M. Onysko, I.V. Chelpanova   +2 more
openaire   +3 more sources

Computational modeling of growth: systemic and pulmonary hypertension in the heart [PDF]

, 2010
We introduce a novel constitutive model for growing soft biological tissue and study its performance in two characteristic cases of mechanically induced wall thickening of the heart.
S. Göktepe, Rausch, M. K., Göktepe, Serdar, Abilez, O. J., Dam, A., Kuhl, E., E. Kuhl, M. K. Rausch, O. J. Abilez, A. Dam   +9 more
core   +1 more source

Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues

npj Microgravity
While the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and its mechanisms remain unclear. In this study, we developed a microphysiological system of engineered muscle
Zhanping Ren, Eun Hyun Ahn, Minjae Do, Devin B. Mair, Amir Monemianesfahani, Peter H. U. Lee, Deok-Ho Kim   +6 more
doaj   +1 more source

Protection from muscle damage in the absence of changes in muscle mechanical behavior

, 2016
Introduction: The repeated bout effect characterizes the protective adaptation after a single bout of unaccustomed eccentric exercise that induces muscle damage. Sarcomerogenesis and increased tendon compliance have been suggested as potential mechanisms
Cresswell, Andrew G., Hoffman, Ben W., Carroll, Timothy J., Lichtwark, Glen A.   +3 more
core   +1 more source