Results 131 to 140 of about 42,516 (245)

Sarcoplasmic reticulum-mitochondria microdomains: hugging and kissing in the heart. [PDF]

Am J Physiol Cell Physiol
Jhun BS, O-Uchi J, Rhee B, Ahrari A, DeMichaelis N, Jeon KI, Booth DM, Sheu SS.   +7 more
europepmc   +1 more source

Primitive Phospholamban- and Sarcolipin-like Peptides Inhibit the Sarcoplasmic Reticulum Calcium Pump SERCA. [PDF]

Biochemistry, 2022
Bak JJ, Aguayo-Ortiz R, Rathod N, Primeau JO, Khan MB, Robia SL, Lemieux MJ, Espinoza-Fonseca LM, Young HS.   +8 more
europepmc   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

TRIC-A Facilitates Sarcoplasmic Reticulum-Mitochondrial Ca²⁺ Signaling Crosstalk in Cardiomyocytes. [PDF]

Cells
Li A, Zhou X, Park KH, Yi J, Li X, Ko JK, Chen Y, Nishi M, Yamazaki D, Takeshima H, Zhou J, Ma J.   +11 more
europepmc   +1 more source

Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice. [PDF]

Physiol Rep, 2022
Yamamoto H, Eshima H, Kakehi S, Kawamori R, Watada H, Tamura Y.   +5 more
europepmc   +1 more source

Sarcoplasmic Reticulum [PDF]

, 2020
openaire   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Functionally Isolated Sarcoplasmic Reticulum in Cardiomyocytes: Experimental and Mathematical Models. [PDF]

Bioengineering (Basel)
Soriano DC, Bassani RA, Bassani JWM.
europepmc   +1 more source

Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse. [PDF]

Front Physiol, 2021
Edwards AG, Mørk H, Stokke MK, Lipsett DB, Sjaastad I, Richard S, Sejersted OM, Louch WE.   +7 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source