Results 141 to 150 of about 42,516 (245)

Protocol for Enrichment of Murine Cardiac Junctional Sarcoplasmic Reticulum Vesicles for Mass Spectrometry Analysis. [PDF]

Int J Mol Sci
Di Antonio C, Marabelli C, Bongianino R, Priori SG.   +3 more
europepmc   +1 more source

Alterations of sarcoplasmic reticulum-mediated Ca²⁺ uptake in a model of premature ventricular contraction (PVC)-induced cardiomyopathy. [PDF]

Mol Cell Biochem, 2023
Balderas-Villalobos J, Medina-Contreras JML, Lynch C, Kabadi R, Ramirez RJ, Tan AY, Kaszala K, Samsó M, Huizar JF, Eltit JM.   +9 more
europepmc   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

The Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana, Collin Matsumoto, L. Fernando Santana   +2 more
wiley   +1 more source

Ultrastructure analysis of mitochondria, lipid droplet and sarcoplasmic reticulum apposition in human heart failure. [PDF]

J Mol Cell Cardiol Plus
Latchman NR, Stevens TL, Bedi KC, Prosser BL, Margulies KB, Elrod JW.   +5 more
europepmc   +1 more source

Electrostatic interactions between single arginine and phospholipids modulate physiological properties of sarcoplasmic reticulum Ca²⁺-ATPase. [PDF]

Sci Rep, 2022
Yamasaki K, Daiho T, Yasuda S, Danko S, Kawabe JI, Suzuki H.   +5 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Highly Oligomeric DRP1 Strategic Positioning at Mitochondria-Sarcoplasmic Reticulum Contacts in Adult Murine Heart Through ACTIN Anchoring. [PDF]

Cells
Fernandez-Sanz C, De la Fuente S, Nichtova Z, Federico M, Duvezin-Caubet S, Lanvermann S, Tsai HY, Xin Y, Csordas G, Wang W, Mourier A, Sheu SS.   +11 more
europepmc   +1 more source

Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. [PDF]

Nat Cardiovasc Res, 2022
Macías Á, González-Guerra A, Moreno-Manuel AI, Cruz FM, Gutiérrez LK, García-Quintáns N, Roche-Molina M, Bermúdez-Jiménez F, Andrés V, Vera-Pedrosa ML, Martínez-Carrascoso I, Bernal JA, Jalife J.   +12 more
europepmc   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

Modeling sarcoplasmic reticulum Ca²⁺ in rat cardiomyocytes. [PDF]

Biophys Rep
Su Y, Liang Y, Xu M, Gao B, Zhang S, Yang E, Yin S, Li D, Huang Z, Xie W.   +9 more
europepmc   +1 more source