Results 161 to 170 of about 140,542 (289)

Integrins Increase Sarcoplasmic Reticulum Activity for Excitation-Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes. [PDF]

Int J Mol Sci, 2022
Wang BX, Kane C, Nicastro L, King O, Kit-Anan W, Downing B, Deidda G, Couch LS, Pinali C, Mitraki A, MacLeod KT, Terracciano CM.   +11 more
europepmc   +1 more source

Calcium release from sarcoplasmic reticulum of normal and dystrophic mice.

, 1984
Contraction of skeletal muscle is triggered by release of calcium from the sarcoplasmic reticulum. In this study, highly purified normal and dystrophic mouse sarcoplasmic reticulum vesicles were compared with respect to calcium release characteristics ...
VOLPE, POMPEO, Mrak RE, Costello B, Fleischer S.   +3 more
core  

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Structure-function relationships and modifications of cardiac sarcoplasmic reticulum Ca2+-transport. [PDF]

Physiol Res, 2021
Nusier M, Shah AK, Dhalla NS.
europepmc   +1 more source

Sedentary ageing remodels the structure–function relationships that underlie calcium signalling at super‐resolution scales in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of calcium spark function and ryanodine receptor (RyR) structure within a sedentary model of ageing. Upon sympathetic stimulation from 1 µM isoprenaline a linear response to calcium spark morphology occurred, accompanied by a biphasic progression of RyR remodelling across age.
Miriam E. Hurley, David Conesa, Alan P. Benson, Michael A. Colman   +3 more
wiley   +1 more source

Cylindrical Crystallization of Ca²⁺-ATPase and Its Potential Role in Sarcoplasmic Reticulum Dynamics. [PDF]

Int J Mol Sci
Nakamura J, Tajima G, Suwa M, Sato C.
europepmc   +1 more source

Diving into the unknown: Evidence of enhanced skeletal muscle lactate efflux potential and blood–muscle exchange in competitive breath‐hold divers

The Journal of Physiology, EarlyView.
Abstract figure legend Competitive breath‐hold divers exhibit skeletal muscle characteristics indicative of enhanced blood‐muscle exchange capacity and increased lactate efflux potential. Top left: Participant characteristics, matched for age, height, body mass, and maximal oxygen uptake (V̇O2max${\dot{\mathrm{V}}}\rm{O}_{\rm{2max}}$).
Antonis Elia, Matthew Lees, John O'Hara, Nathan Hodson, Jordan Acheson, Oliver Wilson, Paul Parker, Matthew Barlow   +7 more
wiley   +1 more source

Sarcoplasmic reticulum-mitochondria microdomains: hugging and kissing in the heart. [PDF]

Am J Physiol Cell Physiol
Jhun BS, O-Uchi J, Rhee B, Ahrari A, DeMichaelis N, Jeon KI, Booth DM, Sheu SS.   +7 more
europepmc   +1 more source

Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse. [PDF]

Front Physiol, 2021
Edwards AG, Mørk H, Stokke MK, Lipsett DB, Sjaastad I, Richard S, Sejersted OM, Louch WE.   +7 more
europepmc   +1 more source

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source