Results 181 to 190 of about 140,542 (289)

Ultrastructure analysis of mitochondria, lipid droplet and sarcoplasmic reticulum apposition in human heart failure. [PDF]

J Mol Cell Cardiol Plus
Latchman NR, Stevens TL, Bedi KC, Prosser BL, Margulies KB, Elrod JW.   +5 more
europepmc   +1 more source

Electrostatic interactions between single arginine and phospholipids modulate physiological properties of sarcoplasmic reticulum Ca²⁺-ATPase. [PDF]

Sci Rep, 2022
Yamasaki K, Daiho T, Yasuda S, Danko S, Kawabe JI, Suzuki H.   +5 more
europepmc   +1 more source

Intracellular mechanosensation in intestinal smooth muscle: Piezo1 complexes amplify signalling beyond the surface

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanosensation is not confined to the cell surface. In intestinal smooth muscle Piezo1 is predominantly intracellular (86%), where it forms a nanoscale (<40 nm) complex at the sarcoplasmic reticulum (SR)–plasma membrane junction. Within this sensor–amplifier–effector axis intra‐Piezo1 is the sensor that detects force at the SR,
Geoanna M. Bautista, Declan Manning, Emily C. Lieu, Stephanie I. Ugochukwu, Collin Matsumoto, Joshua P. Tulman, Miguel Martin‐Aragon Baudel, Nuria Daghbouche‐Rubio, Steven J. McElroy, Sal A. Baker, Manuel F. Navedo, L. Fernando Santana   +11 more
wiley   +1 more source

Highly Oligomeric DRP1 Strategic Positioning at Mitochondria-Sarcoplasmic Reticulum Contacts in Adult Murine Heart Through ACTIN Anchoring. [PDF]

Cells
Fernandez-Sanz C, De la Fuente S, Nichtova Z, Federico M, Duvezin-Caubet S, Lanvermann S, Tsai HY, Xin Y, Csordas G, Wang W, Mourier A, Sheu SS.   +11 more
europepmc   +1 more source

Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. [PDF]

Nat Cardiovasc Res, 2022
Macías Á, González-Guerra A, Moreno-Manuel AI, Cruz FM, Gutiérrez LK, García-Quintáns N, Roche-Molina M, Bermúdez-Jiménez F, Andrés V, Vera-Pedrosa ML, Martínez-Carrascoso I, Bernal JA, Jalife J.   +12 more
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Modeling sarcoplasmic reticulum Ca²⁺ in rat cardiomyocytes. [PDF]

Biophys Rep
Su Y, Liang Y, Xu M, Gao B, Zhang S, Yang E, Yin S, Li D, Huang Z, Xie W.   +9 more
europepmc   +1 more source

PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca²⁺ Leak in Smooth Muscle Cells. [PDF]

Front Physiol, 2022
Dagnino-Acosta A, Guerrero-Hernandez A.
europepmc   +1 more source

A NEW CONFIGURATION OF THE SARCOPLASMIC RETICULUM [PDF]

The Journal of Cell Biology, 1964
openaire   +2 more sources

Long AKAP18 isoforms anchor ubiquitin specific proteinases and coordinate calcium reuptake at the sarcoplasmic reticulum. [PDF]

J Biol Chem
Park T, Forbush K, Li Y, Vivas O, Rosenthal KJ, Falcone J, Wong CJ, Bruce JE, Moreno C, Dessauer CW, Scott JD.   +10 more
europepmc   +1 more source