Results 191 to 200 of about 140,542 (289)

Disruption of Sarcoplasmic Reticulum-Mitochondrial Contacts Underlies Contractile Dysfunction in Experimental and Human Atrial Fibrillation: A Key Role of Mitofusin 2. [PDF]

J Am Heart Assoc, 2022
Li J, Qi X, Ramos KS, Lanters E, Keijer J, de Groot N, Brundel B, Zhang D.   +7 more
europepmc   +1 more source

β‐hydroxy‐β‐methylbutyrate improves fast‐twitch muscle function, histopathology and mitochondrial respiration in the D2.mdx dystrophic mouse

The Journal of Physiology, EarlyView.
Abstract figure legend β‐Hydroxy‐β‐methylbutyrate (HMB) enhances fast‐twitch muscle and mitochondrial function in D2.mdx mice. Male DBA/2J (wild‐type) and D2.mdx mice aged 3 or 6 months received daily β‐hydroxy‐β‐methylbutyrate (HMB; 1 mg g−1 day−1) via drinking water for 8 weeks. Fast‐twitch extensor digitorum longus (EDL) and slow‐twitch soleus (SOL)
Nicholas Giourmas, Hannah Lalunio, Memphis Calzoni, Ryan Bagaric, Craig A. Goodman, Alan Hayes   +5 more
wiley   +1 more source

Assaying sarcoplasmic reticulum Ca²⁺-leak in mouse atrial myocytes. [PDF]

Biophys Rep
Xu F, Li JJ, Yang E, Zhang Y, Xie W.
europepmc   +1 more source

Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice. [PDF]

NPJ Microgravity, 2022
Khan AA, Gul MT, Karim A, Ranade A, Azeem M, Ibrahim Z, Ramachandran G, Nair VA, Ahmad F, Elmoselhi A, Qaisar R.   +10 more
europepmc   +1 more source

Macroscopic to ultrastructural analyses identify the loss of myofibrils as the primary mediator of ageing‐ and disuse‐induced muscle fibre atrophy

The Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle structure was analysed at three levels in young vs. aged humans, and in young vs. aged mice subjected to unilateral hindlimb immobilization to model disuse. (1) Macroscopic: magnetic resonance imaging of the thigh (human) and wet mass of individual hindlimb muscles (mouse) revealed that both ageing and disuse ...
Ramy K. A. Sayed, Anthony N. Lange, Hector G. Paez, Jamie E. Hibbert, Marius Meinhold, Corey G. K. Flynn, Jared Hartung, Matilde B. Z. Santibanez, Isabell Dobrzycki, David J. Wrucke, Carlos S. Zepeda, Jessica J. James, Christopher W. Sundberg, Troy A. Hornberger   +13 more
wiley   +1 more source

Wnt/β-catenin pathway induces cardiac dysfunction via AKAP6-mediated RyR2 phosphorylation and sarcoplasmic reticulum calcium leakage. [PDF]

J Mol Cell Biol
Li A, Shen Y, Li Z, Li L.
europepmc   +1 more source

Cardiac Resynchronization and Circulating Markers of Sarcoplasmic Reticulum Calcium Handling and Sudden Death Risk. [PDF]

JACC Clin Electrophysiol, 2021
Jiang N, Zhou A, Imran H, Shi G, Kaseer B, Siu V, Chu AF, Donaldson DM, Kirk MM, Philips BB, Dudley SC.   +10 more
europepmc   +1 more source

Renin‐Angiotensin Signaling and Vascular Function: Insights into Health and Disease

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT The renin‐angiotensin system (RAS) is an essential regulator of vascular structure and function, and dysregulation of angiotensin II (Ang II) signaling plays a critical role in the development of hypertension and associated vascular complications.
Giovanni Bertoldi, Swapnil K. Sonkusare
wiley   +1 more source

Intercellular NETwork-facilitated sarcoplasmic reticulum targeting for myocardial ischemia-reperfusion injury treatment. [PDF]

Sci Adv
Jiang P, Huang F, Chen L, Zhou H, Deng Y, Li L, Chen M, Huang Y.   +7 more
europepmc   +1 more source

Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia. [PDF]

J Mol Cell Cardiol, 2021
Hamilton S, Terentyeva R, Clements RT, Belevych AE, Terentyev D.   +4 more
europepmc   +1 more source