Results 51 to 60 of about 140,297 (191)

Targeting the calcium ATPase to the endoplasmic reticulum

, 2009
The sarco/endoplasmic reticulum calcium ATPase (SERCA) pumps calcium from thecytoplasm into the lumen of the endoplasmic or sarcoplasmic reticulum (ER/SR), removingexcess Ca2+ from the cytoplasm and replenishing ER/SR Ca2+ stores. SERCA is located inboth
Watson, Helen Rachel
core   +1 more source

Investigating PKD2 deficiency-associated cardiomyopathies using hESC-cardiomyocytes and bioengineered 3D ventricular cardiac tissue strips

Cell Death and Disease
Autosomal dominant polycystic kidney disease is a highly prevalent hereditary renal disorder caused by mutations in either polycystin-1 or polycystin-2. These patients also develop cardiomyopathies.
Jingxuan Li, Wentao Peng, Maxwell Kwok, Huanyu Ding, Duan Zhuo, Bimal Gurung, Ishan Raj Lakhani, Hongyan Yu, Ellen N. Poon, Ronald A. Li, Xiaoqiang Yao   +10 more
doaj   +1 more source

Emerging Evidence for cAMP-calcium Cross Talk in Heart Atrial Nanodomains Where IP-Evoked Calcium Release Stimulates Adenylyl Cyclases

Contact, 2021
Calcium handling is vital to normal physiological function in the heart. Human atrial arrhythmias, eg. atrial fibrillation, are a major morbidity and mortality burden, yet major gaps remain in our understanding of how calcium signaling pathways function ...
Rebecca-Ann B. Burton, Derek A. Terrar
doaj   +1 more source

The identification of sarcoplasmic reticulum terminal cisternae proteins in platelets [PDF]

, 1989
Two new proteins with apparent molecular masses of 53 kDa and 190 kDa have been identified in both sarcoplasmic reticulum and human blood platelets using a monoclonal antibody, FII1b5.
Barton, D W, White, G C, White, T E, Krause, K H, Campbell, K P, Fischer, T H   +5 more
core   +1 more source

ULTRASTRUCTURE OF SARCOPLASMIC RETICULUM PREPARATIONS [PDF]

The Journal of Cell Biology, 1969
Fragmented sarcoplasmic reticulum (FSR) from rabbit muscle was examined by positive staining, negative staining, and freeze-etch electron microscopic techniques in the absence and presence of calcium transport conditions. The existence of 30–40 A particles covering the outer surface of FSR vesicles was confirmed by two different negative stains in ...
D W, Deamer, R J, Baskin
openaire   +2 more sources

Energy interconversion by the sarcoplasmic reticulum Ca2+-ATPase: ATP hydrolysis, Ca2+ transport, ATP synthesis and heat production

Anais da Academia Brasileira de Ciências, 2000
The sarcoplasmic reticulum of skeletal muscle retains a membrane bound Ca2+-ATPase which is able to interconvert different forms of energy. A part of the chemical energy released during ATP hydrolysis is converted into heat and in the bibliography it is ...
LEOPOLDO DE MEIS
doaj   +1 more source

Illuminating Sarcoplasmic Reticulum Calcium [PDF]

Circulation Research, 2003
The bulk of the Ca2+ that activates contraction in the heart comes from the sarcoplasmic reticulum (SR). Calcium is released by the process of Ca2+-induced Ca2+ release (CICR) in which the entry of a small amount of Ca2+ across the cell membrane triggers the release of much more from the SR.
Venetucci, L., Trafford, A. W.; id_orcid 0000-0002-2770-445X, Eisner, D. A.   +2 more
openaire   +1 more source

Molecular cloning of the high affinity calcium binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum

, 1989
A cDNA clone encoding the high affinity Ca2+-binding protein (HACBP) of rabbit skeletal muscle sarcoplasmic reticulum was isolated and sequenced. The cDNA encoded a protein of 418 amino acids, but a comparison of the deduced amino acid sequence with the ...
Reithmeier, F. A. F., MacLennan, D. H., Burns, K., Michalak, M., Fliegel, Larry   +4 more
core   +1 more source

The reaction of N-(1-pyrene)maleimide with sarcoplasmic reticulum [PDF]

, 1986
The excimer fluorescence of the adduct of N-(1-pyrene)maleimide (PMI) with the Ca2+-ATPase was proposed as a probe of ATPase-ATPase interactions in sarcoplasmic reticulum (Lüdi and Hasselbach, Eur. J. Biochem., 1983, 130:5–8).
Martonosi, A., Papp, S., Joshi, N., Kracke, G.   +3 more
core   +1 more source

Developmental Changes in the Excitation–Contraction Mechanisms of the Ventricular Myocardium and Their Sympathetic Regulation in Small Experimental Animals

Journal of Cardiovascular Development and Disease
The developmental changes in the excitation–contraction mechanisms of the ventricular myocardium of small animals (guinea pig, rat, mouse) and their sympathetic regulation will be summarized.
Shogo Hamaguchi, Naoki Agata, Maika Seki, Iyuki Namekata, Hikaru Tanaka   +4 more
doaj   +1 more source