Results 61 to 70 of about 140,297 (191)

Differentiation of sarcoplasmic reticulum during cardiac myogenesis

open access: yes, 1987
The composition and function of fetal and mature sheep cardiac sarcoplasmic reticulum membranes were investigated. Phospholamban, a major phosphoprotein in the mature sarcoplasmic reticulum membranes, was present in early stages of cardiac myogenesis ...
W. Pegg, M. Michalak
core   +1 more source

Functional effects of mutations in the skeletal muscle ryanodine receptor type 1 (RYR1) linked to malignant hyperthermia and central core disease [PDF]

open access: yes, 2006
Malignant hyperthermia (MH) is a pharmacogenetic disorder with autosomal dominant inheritance. In susceptible individuals, a MH crisis may be triggered by commonly used halogenated anaesthetics (halothane, isoflurane) or muscle relaxants ...
Ducreux, Sylvie
core   +1 more source

Effects of Manual Acupuncture and Electroacupuncture on Ca~(2+) Content and Ca~(2+)-ATPase Activity in Sarcoplasmic Reticulum of Skeletal Muscle Cells in Rats During Acute Swimming Exercise

open access: yes针刺研究, 2008
Objective To observe the effects of manual acupuncture(MA) and electroacupuncture(EA) on Ca2+ content and Ca2+-ATPase activity in sarcoplasmic reticulum of skeletal muscle cells in rats of acute swimming exercise(ASE) so as to reveal its underlying ...
GAO Ming   +4 more
doaj  

Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light

open access: yesFrontiers in Neuroscience, 2018
As one of the ubiquitous second messengers, the intracellular Ca2+, has been revealed to be a pivotal regulator of various cellular functions. Two major sources are involved in the initiation of Ca2+-dependent signals: influx from the extracellular space
Toshifumi Asano   +4 more
doaj   +1 more source

The Ultrastructure of Developing Sarcoplasmic Reticulum

open access: yesJournal of Biological Chemistry, 1974
Developmental changes in the sarcoplasmic reticulum and surface membranes of chicken skeletal muscles were investigated by electron microscopy. A dominant feature of freeze-etched sarcoplasmic reticulum membranes isolated from adult animals is the presence of spherical intramembranous particles of 75 A apparent diameter which are more numerous on the ...
T W, Tillack, R, Boland, A, Martonosi
openaire   +2 more sources

Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum

open access: yes, 1990
A cDNA clone encoding 55-kDa multifunctional, thyroid hormone binding protein of rabbit skeletal muscle sarcoplasmic reticulum was isolated and sequenced.
Burns, K.   +3 more
core   +1 more source

An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle [PDF]

open access: yes, 2007
Previous investigations on pulmonary artery smooth muscle cells have shown that nicotinic acid adenine dinucleotide diphosphate (NAADP) evokes highly localised intracellular Ca²⁺ bursts by mobilising thapsigargin-insensitive Ca²⁺ stores.
Kinnear, Nicholas P.
core   +2 more sources

Impaired Sarcoplasmic Reticulum Calcium Uptake and Release Promote Electromechanically and Spatially Discordant Alternans: A Computational Study

open access: yes, 2016
Cardiac electrical dynamics are governed by cellular-level properties, such as action potential duration (APD) restitution and intracellular calcium (Ca) handling, and tissue-level properties, including conduction velocity restitution and cell–cell ...
Seth H. Weinberg
core   +1 more source

Calcium sparks in arterial smooth muscle cells regulate vascular tone

open access: yesJournal of Biological Research, 2002
It is named Ca2+ sparks a local, rapid and transient Ca2+ release from sarcoplasmic reticulum (SR) by the opening of ryanodine-sensitive (RyR) channels. RyR channels localized in SR are found in all muscle cell types (cardiac, skeletal, smooth) and many
Maurizio Mandalà
doaj   +1 more source

Impact of an electric field on P-type ATPases [PDF]

open access: yes, 2008
P-type ATPases are membrane proteins acting as ion pumps that drive an active transport of cations across the membrane against a concentration gradient. The required energy for the ion transport is provided by binding and hydrolysis of ATP.
Weidemüller, Christian, Hauser, Karin
core   +1 more source

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