Possible inhibition of GM-CSF production by SARS-CoV-2 spike-based vaccines
Molecular Medicine, 2021 A SARS-like coronavirus 2 (SARS-CoV-2) has caused a pandemic Coronavirus Disease 2019 (COVID-19) that killed more than 3.3 million people worldwide. Like the SARS-CoV, SARS-CoV-2 also employs a receptor-binding motif (RBM) of its spike protein to bind a ...
Jianhua Li +3 more
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Proteolytic activation of SARS‐CoV‐2 spike protein
Microbiology and Immunology, 2021 Abstract Spike (S) protein cleavage is a crucial step in coronavirus infection. In this review, this process is discussed, with particular focus on the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
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Calreticulin Regulates SARS-CoV-2 Spike Protein Turnover and Modulates SARS-CoV-2 Infectivity
Cells, 2023 Cardiovascular complications are major clinical hallmarks of acute and post-acute coronavirus disease 2019 (COVID-19). However, the mechanistic details of SARS-CoV-2 infectivity of endothelial cells remain largely unknown. Here, we demonstrate that the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) protein shares a similarity with the ...
Nader Rahimi +7 more
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Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH-and Cysteine Protease-Independent Fc gamma R Pathway [PDF]
, 2011 Copyright © 2011, American Society for Microbiology. All Rights Reserved.Public health measures successfully contained outbreaks of the severe acute respiratory syndrome coronavirus (SARS-CoV) infection.
Cheung, Chung y +40 more
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, 2021 Proposed algorithm integrating anti-SARS-CoV-2 Spike-Protein-RBD antibody monitoring to manage dialysis centers.
Jean-Philippe Bourdenx (11524599) +6 more
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Engineered extracellular vesicles directed to the spike protein inhibit SARS-CoV-2 [PDF]
, 2022 SARS-CoV-2 (CoV-2) viral infection results in COVID-19 disease, which has caused significant morbidity and mortality worldwide. A vaccine is crucial to curtail the spread of SARS-CoV-2, while therapeutics will be required to treat ongoing and reemerging ...
Supramaniam, Aroon +21 more
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Frontiers in Immunology, 2022 Since first reported in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly acquiring mutations, particularly in the spike protein, that can modulate pathogenicity, transmission and antibody evasion leading to successive waves ...
Mohanraj Manangeeswaran +13 more
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Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]
, 2012 © 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Béatrice Nal +66 more
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SARS-CoV-2 variants, lineage classification and mutations on the Spike protein sequence.
, 2023 SARS-CoV-2 variants, lineage classification and mutations on the Spike protein sequence.
Ugo Lomoio (16624608) +4 more
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Rotavirus as an Expression Platform of the SARS-CoV-2 Spike Protein [PDF]
, 2021 Abstract Rotavirus, a segmented double-stranded RNA virus, is a major cause of acute gastroenteritis in young children. The introduction of live oral rotavirus vaccines has reduced the incidence of rotavirus disease in many countries.
Asha A. Philip, John T. Patton
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