Results 41 to 50 of about 99,522,423 (293)

SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes

Frontiers in Public Health, 2023
ImportanceIn the absence of evidence of clinical utility, the United States' Centers for Disease Control and Prevention does not currently recommend the assessment of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike-protein antibody ...
Harvey W. Kaufman, Stanley Letovsky, William A. Meyer, Laura Gillim, Magdalene M. Assimon, Carly A. Kabelac, John W. Kroner, Shannon L. Reynolds, Marcia Eisenberg   +8 more
doaj   +1 more source

Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]

, 2006
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Cox Freek, Doerr, Hans Wilhelm, Brink, Edward van den, van den Brink Edward N, Hans Wilhelm Doerr, ter Meulen Jan, Doerr Hans Wilhelm, Cheung, Chung Y., de Kruif John, Jaap Goudsmit, Leo L. M., Poon, Leo L M Poon, Marissen Wilfred E, Marissen, Wilfred E., Poon Leo L. M, Chow Vincent T, Chung Y Cheung, Wolfgang Preiser, Preiser, Wolfgang, Van Deventer, E, Bogaards Johannes A, Freek Cox, Wilfred E Marissen, Els van Deventer, Joseph S M Peiris, Chow, Tak-Kwong Vincent, Bakker, Arjen Q., Leung, CSW, Goudsmit Jaap, Deventer, Els van, Kruif, John de, De Kruif, J, John de Kruif, Cynthia S W Leung, Jan ter Meulen, Bogaards, Johannes A., Cox, F, Preiser Wolfgang, Cox, Freek, Goudsmit, J, Peiris Joseph S. M, Poon, LLM, Cheung, CY, Johannes A Bogaards, Doerr, HW, van Deventer Els, Marissen, WE, Bakker Arjen Q, Leung Cynthia S. W, Chow, VT, Edward N van den Brink, Bogaards, JA, Vincent T Chow, Arjen Q Bakker, Cheung Chung Y, Van Den Brink, EN, Peiris, Joseph Sriyal Malik, Ter Meulen, J, Leung, Cynthia S. W., Goudsmit, Jaap, Peiris, JSM, Meulen, Jan ter, Bakker, AQ, Preiser, W, Poon L.L.M., Van Den Brink E.N., Preiser W., Leung C.S.W., Marissen W.E., Chow V.T., Bakker A.Q., Bogaards J.A., Goudsmit J., Van Deventer E., Doerr H.W., Cheung C.Y., Ter Meulen J., Peiris J.S.M., Cox F., De Kruif J.   +79 more
core   +1 more source

Anti-SARS-CoV-2 spike protein antibody titer and neutralizing activity.

, 2022
Anti-SARS-CoV-2 spike protein antibody titer and neutralizing activity.
Masaharu Tsubokura (394788), Takeshi Kawamura (183920), Yudai Kaneko (12859357), Yurie Kobashi (9039879), Yoshitaka Nishikawa (735511), Fumiya Omata (12859354), Yuzo Shimazu (12859351), Tatsuhiko Kodama (200284)   +7 more
core   +1 more source

Evaluation of spike protein antigens for SARS-CoV-2 serology

Journal of Virological Methods, 2021
Abstract Background Spike protein domains are being used in various serology-based assays to detect prior exposure to SARS-CoV-2 virus. However, there has been limited comparison of human antibody titers against various spike protein antigens among COVID-19 infected patients.
Suraj Jagtap, Ratnasri K, Priyanka Valloly, Rakhi Sharma, Satyaghosh Maurya, Anushree Gaigore, Chitra Ardhya, Dayananda S. Biligi, Bapu Koundinya Desiraju, Uma Chandra Mouli Natchu, Deepak Kumar Saini, Rahul Roy   +11 more
openaire   +3 more sources

Flowchart of patient receiving BNT162b2-mRNA vaccines and analysed for IgG anti-SARS-CoV-2 Spike-Protein-RBD.

, 2021
Flowchart of patient receiving BNT162b2-mRNA vaccines and analysed for IgG anti-SARS-CoV-2 Spike-Protein-RBD.
Jean-Philippe Bourdenx (11524599), Philippe Martin-Dupont (11524605), Thomas Bachelet (4164613), Antoine Pommereau (11524611), Charlie Martinez (11524602), Simon Mucha (6437372), Valerie Perier (11524608)   +6 more
core   +1 more source

Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein

Frontiers in Chemistry, 2021
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still an emergent pandemic for humans. The virus infection is achieved by penetrating its spike protein to host cells via binding with ACE2.
Bingqian Li, Bingqian Li, Lin Wang, Huan Ge, Xianglei Zhang, Penxuan Ren, Yu Guo, Wuyan Chen, Jie Li, Wei Zhu, Wenzhang Chen, Lili Zhu, Fang Bai   +12 more
doaj   +1 more source

Stability and expression of SARS-CoV-2 spike-protein mutations

Molecular and Cellular Biochemistry, 2022
Abstract Protein fold stability likely plays a role in SARS-CoV-2 S-protein evolution, together with ACE2 binding and antibody evasion. While few thermodynamic stability data are available for S-protein mutants, many systematic experimental data exist for their expression.
Kristoffer T. Bæk, Rukmankesh Mehra, Kasper P. Kepp   +2 more
openaire   +2 more sources

SARS-CoV-2 Spike Protein Destabilizes Microvascular Homeostasis

Microbiology Spectrum, 2021
SARS-CoV-2 causes complex effects on microvascular homeostasis that potentially contribute to organ dysfunction and coagulopathies. SARS-CoV-2 binds to, and causes downregulation of angiotensin converting enzyme 2 (ACE2) on cells that it infects.
Soumya Panigrahi, Tamal Goswami, Brian Ferrari, Christopher J. Antonelli, Douglas A. Bazdar, Hannah Gilmore, Michael L. Freeman, Michael M. Lederman, Scott F. Sieg   +8 more
openaire   +3 more sources

Proyecto Argentino Interinstitucional de genómica de SARS-CoV-2. Reporte Nº 1 Inicial. “Análisis de secuencias de SARS-CoV-2 obtenidas de pacientes con COVID-19 de Argentina” [PDF]

, 2020
Hasta el 9 de septiembre 2021 el Proyecto a generado 26 Reportes. Reporte nro 1 - Análisis inicial. Reporte nro 2 – Patagonia. Reportes nro 3 y 4 - CABA y Prov. BsAs. Reporte nro 5 – Córdoba. Reporte nro 6 – Chaco. Reporte UK.
Consorcio Argentino de Genómica de SARS-CoV-2
core   +1 more source

Protocol to isolate and assess spike protein cleavage in SARS-CoV-2 variants obtained from clinical COVID-19 samples

STAR Protocols, 2022
Summary: For efficient cell entry, SARS-CoV-2 spike protein needs to be cleaved by cellular proteases. Here, we present a comprehensive protocol to assess SARS-CoV-2 spike protein cleavage in viral supernatants from SARS-CoV-2-infected cells.
Alba Escalera, Adolfo García-Sastre, Teresa Aydillo   +2 more
doaj   +1 more source